Unfortunately, no studies were performed using Diprotin A in blood samples. It is recommended to review the scientific literature. Please see the link below.
https://scholar.google.com/scholar?hl=en&as_sdt=0%2C26&q=What+is+the+final+concentration+of+Diprotin+A++necessary+for+avoiding+GLP-1+degradation+in+blood+samples&btnG=
D3822
Dipeptidyl Peptidase IV Inhibitor I
≥95% (HPLC), glucagon-like peptide (GLP-1) modulator, solid
Synonym(s):
Diprotin A
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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Check Cart for Availability | $284.00 |
About This Item
Empirical Formula (Hill Notation):
C17H31N3O4
Molecular Weight:
341.45
UNSPSC Code:
12352202
NACRES:
NA.77
Assay:
≥95% (HPLC)
Product Name
Dipeptidyl Peptidase IV Inhibitor I,
assay
≥95% (HPLC)
Quality Segment
form
solid
color
white
storage temp.
2-8°C
General description
Dipeptidyl peptidase IV (DPP IV) is a member of the prolyl-specific proteases family. It is a dimeric type II integral membrane glycoprotein that is broadly expressed in the epithelial and nonepithelial tissues. It is majorly expressed in the kidney and the colon.PMID 24099035
Application
Dipeptidyl peptidase IV inhibitor I has been used in acute in vivo studies to assess rapid plasma glucagon-like peptide (GLP-1) responses to specified secretory agents in mice.[1]
Biochem/physiol Actions
Dipeptidyl peptidase IV (DPP IV) functions as a modulator of glucagon-like peptide (GLP-1), insulin-stimulating hormones, and glucose-dependent insulinotropic polypeptide (GIP). It is an essential therapeutic target for type 2 diabetes (T2DM).PMID 19149538 DPP-4 inhibitors are crucial for maintaining glucose homeostasis by prolonging the activity of GLP-1 and GIP. They also enhance glycemic control for a longer period when compared to early oral hypoglycemics.PMID 29692250 DPP-4 also acts as a binding protein and a ligand of extracellular factors.PMID 32506195
Other Notes
Ile-Pro-Ile
1 of 1
This Item | |||
|---|---|---|---|
| description - | description - | description The Dipeptidylpeptidase IV Inhibitor I controls the biological activity of Dipeptidylpeptidase IV. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. | description recombinant, expressed in Sf9 cells |
| assay ≥95% (HPLC) | assay - | assay ≥95% (HPLC) | assay - |
| form solid | form solution | form amorphous solid | form solution |
| storage temp. 2-8°C | storage temp. - | storage temp. 2-8°C | storage temp. −70°C |
| Quality Level 200 | Quality Level 100 | Quality Level 100 | Quality Level 200 |
| color white | color - | color white | color - |
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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What is the final concentration of Diprotin A (D3822) necessary for avoiding GLP-1 degradation in blood samples?
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