C7278
Caseinoglycopeptide from bovine casein
essentially salt-free, lyophilized powder
Synonym(s):
Bovine Casein Glycopeptide
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About This Item
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form
essentially salt-free, lyophilized powder
mol wt
~7000
technique(s)
affinity chromatography: suitable
color
white
UniProt accession no.
storage temp.
2-8°C
Gene Information
cow ... CSN3(281728)
Amino Acid Sequence
Met-Ala-Ile-Pro-Pro-Lys-Lys-Asn-Gln-Asp-Lys
Application
- Bioactive Peptide in Dairy Research: Investigation into the effects of bovine caseinoglycopeptide on CD4+ T cells showcased its potential to modulate immune responses, highlighting its application in nutrition and functional food development (Otani et al., 1996).
Biochem/physiol Actions
The soluble carboxyl-terminal moiety of κ-casein. This antithrombotic peptide binds to glycoprotein GPIb in the platelet membrane, thus inhibiting platelet aggregation by blocking the binding of von Willebrand factor.
Preparation Note
Prepared by a modification of the method of Alais and Jolles.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Certificates of Analysis (COA)
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[Comparative study of the caseinoglycopeptides formed by the action of rennin on caseins from the cow, sheep and goat. II. Study of the non-peptide portion].
Biochimica et biophysica acta, 51, 315-322 (1961-08-05)
Analytical chemistry, 83(12), 4829-4837 (2011-04-30)
The sites of mucin-type O-glycosylation are largely unpredictable, making structural analysis by mass spectrometry (MS) indispensible. On the peptide level, a site localization and characterization of O-linked glycans in situ using tandem MS with electron-transfer dissociation or matrix-assisted laser desorption
Journal of clinical microbiology, 46(12), 3965-3970 (2008-10-24)
Human parechoviruses (HPeV) are widespread pathogens belonging to the Picornavirus family. Six genotypes, which have predominantly been isolated from children, are known. Data on prevalence of HPeV genotypes are generally based on cell culture, which may underestimate the prevalence of
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