C5108
Cathepsin G from human sputum
≥0.2 units/mg protein, salt-free, lyophilized powder
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About This Item
CAS Number:
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.32
Recommended Products
biological source
human sputum
form
salt-free, lyophilized powder
specific activity
≥0.2 units/mg protein
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
Gene Information
human ... CTSG(1511)
Biochem/physiol Actions
Cathepsin G has pro-apoptotic activity and can activate caspases in vitro.
Storage Class
13 - Non Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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E D Son et al.
Dermatology (Basel, Switzerland), 224(4), 352-360 (2012-07-05)
Cathepsin G, a serine protease that is activated by ultraviolet (UV) radiation, increases matrix metalloproteinase-1 (MMP-1) expression in fibroblasts through fibronectin (Fn) fragmentation and promotes the conversion of proMMP-1 to active MMP-1. This study investigated whether [2-[3-[[(1-benzoyl-4-piperidinyl)methylamino]carbonyl]-2-naphthalenyl]-1-(1-naphthalenyl)-2-oxoethyl]-phosphonic acid (KPA), a
Prasad Tongaonkar et al.
PloS one, 7(3), e32469-e32469 (2012-03-27)
The azurophilic granules of human neutrophils contain four α-defensins called human neutrophil peptides (HNPs 1-4). HNPs are tridisulfide-linked antimicrobial peptides involved in the intracellular killing of organisms phagocytosed by neutrophils. The peptides are produced as inactive precursors (proHNPs) which are
Hitoshi Tsujimoto et al.
PloS one, 7(2), e29964-e29964 (2012-03-03)
Black flies (Diptera: Simuliidae) feed on blood, and are important vectors of Onchocerca volvulus, the etiolytic agent of River Blindness. Blood feeding depends on pharmacological properties of saliva, including anticoagulation, but the molecules responsible for this activity have not been
Dawid Dębowski et al.
Peptides, 35(2), 276-284 (2012-04-21)
A series of linear and cyclic fragments and analogs of two peptides (OGTI and HV-BBI) isolated from skin secretions of frogs were synthesized by the solid-phase method. Their inhibitory activity against several serine proteinases: bovine β-trypsin, bovine α-chymotypsin, human leukocyte
Hsiang-Ruei Liao et al.
Biochemical pharmacology, 84(2), 182-191 (2012-04-10)
Respiratory burst mediates crucial bactericidal mechanism in neutrophils. However, undesirable respiratory burst leads to pathological inflammation and tissue damage. This study investigates the effect and the underlying mechanism of 5-hydroxy-7-methoxyflavone (MCL-1), a lignan extracted from the leaves of Muntingia calabura
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