B4153

Boc-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride

Name: Boc-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride
Brand: SIGMA
Price: 483 USD
Availability: InStock

~95%

Synonym(s):

Boc-Gln-Ala-Arg-AMC hydrochloride, Boc-Gln-Ala-Arg-Mca hydrochloride

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5 MG

$483.00

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About This Item

Empirical Formula (Hill Notation):

C₂₉H₄₂N₈O₈ · HCl

CAS Number:

113866-20-9

Molecular Weight:

667.15

NACRES:

NA.32

PubChem Substance ID:

24891756

UNSPSC Code:

12352204

MDL number:

MFCD00080216

Key Documents

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assay

~95%

Quality Level

200

form

powder

solubility

methanol: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

CC(NC(=O)C(CCC(N)=O)NC(=O)OC(C)(C)C)C(=O)NC(CCCNC(N)=N)C(=O)Nc1ccc2C(C)=CC(=O)Oc2c1

InChI

1S/C29H42N8O8/c1-15-13-23(39)44-21-14-17(8-9-18(15)21)35-26(42)19(7-6-12-33-27(31)32)36-24(40)16(2)34-25(41)20(10-11-22(30)38)37-28(43)45-29(3,4)5/h8-9,13-14,16,19-20H,6-7,10-12H2,1-5H3,(H2,30,38)(H,34,41)(H,35,42)(H,36,40)(H,37,43)(H4,31,32,33)

InChI key

LQSLBVXESNRILG-UHFFFAOYSA-N

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Show Differences

1 of 4

This Item	B9385	A3401	T0273
Sigma-Aldrich B4153 Boc-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride	Sigma-Aldrich B9385 Boc-Val-Pro-Arg-7-amido-4-methylcoumarin hydrochloride	A3401 Ala-Ala-Phe-7-amido-4-methylcoumarin	Sigma-Aldrich T0273 N-p-Tosyl-Gly-Pro-Arg 7-amido-4-methylcoumarin hydrochloride
assay ~95%	assay ≥98% (TLC)	assay ≥98% (TLC)	assay ≥98% (TLC)
solubility methanol: 50 mg/mL, clear, colorless	solubility water: 20 mg/mL, clear, colorless	solubility ethanol: 20 mg/mL, clear, colorless to light yellow	solubility acetic acid: 10 mg/mL, clear, colorless
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
form powder	form powder	form powder	form powder
storage temp. −20°C	storage temp. −20°C	storage temp. 2-8°C	storage temp. −20°C

General description

Substrate for trypsin

Boc-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride is a fluorogenic and cell-permeable trypsin substrate.[1]

Application

Boc-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride has been used as a fluorogenic substrate to measure the enzymatic activity of trypsin.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Diel food intake and digestive enzyme production patterns in Solea senegalensis larvae

Navarro-Guillen C, et al.

Aquaculture (Amsterdam, Netherlands), 435, 33-42 (2015)

Morphological and physiological changes of Octopus bimaculoides: from embryo to juvenile

Ibarra-Garcia LE, et al.

Aquaculture (Amsterdam, Netherlands), 497, 364-372 (2018)

Evaluation of fluorogenic substrates in the assessment of digestive enzymes in a decapod crustacean Maja brachydactyla larvae

Rotllant G, et al.

Aquaculture (Amsterdam, Netherlands), 282(1-4), 90-96 (2008)

Digestive biochemistry as indicator of the nutritional status during early development of the long snouted seahorse (Hippocampus reidi)

Novelli B, et al.

Aquaculture (Amsterdam, Netherlands), 464, 196-204 (2016)

Discovery of indole tetrafluorophenoxymethylketone-based potent novel small molecule inhibitors of caspase-3.

Dodheri Syed Samiulla et al.

Organic and medicinal chemistry letters, 2(1), 27-27 (2012-07-17)

Caspase-3 inhibition has been demonstrated to be therapeutically effective in moderating excessive programmed cell death. Interest in caspase-3 as a therapeutic target has led many to pursue the development of inhibitors. To date, only a few series of non-peptide inhibitors

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Global Trade Item Number

SKU	GTIN
B4153-5MG	04061832921303

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Boc-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride