A8292

Acetobromo-α-D-glucuronic acid methyl ester

≥93% (GC)

• Synonym(s): (2,3,4-Tri-O-acetyl-α-D-glucopyranosyl bromide)uronic acid methyl ester, Bromo-2,3,4-tri-O-acetyl-α-D-glucopyranuronic acid methyl ester, Methyl acetobromo-α-D-glucuronate
• Empirical Formula (Hill Notation): C₁₃H₁₇BrO₉
• CAS Number: 21085-72-3
• Molecular Weight: 397.17
• Beilstein/REAXYS Number: 96281
• EC Number: 244-203-4
• MDL number: MFCD00061613
• UNSPSC Code: 12352201
• PubChem Substance ID: 24891328
• NACRES: NA.25

Properties

• assay: ≥93% (GC)
• form: powder
• optical activity: [α]/D 188 to 198 °, c = 1% (w/v) in ethyl acetate
• color: white
• mp: 80-110 °C (lit.)
• solubility: ethyl acetate: 50 mg/mL, clear, colorless to faintly yellow
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: COC(=O)[C@H]1O[C@H](Br)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O
• InChI: 1S/C13H17BrO9/c1-5(15)20-8-9(21-6(2)16)11(13(18)19-4)23-12(14)10(8)22-7(3)17/h8-12H,1-4H3/t8-,9-,10+,11-,12-/m0/s1
• InChI key: GWTNLHGTLIBHHZ-SVNGYHJRSA-N

Description

Application

Acetobromo-α-D-glucuronic acid methyl ester is used for the synthesis of HMR1098-S-Glucuronide Methyl Ester, a new K-ATP-blocking agent being developed as a drug for prevention of sudden cardiac death.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)