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A7165

Sigma-Aldrich

1,5-Anhydro-D-sorbitol

crystalline, ≥98.0% (TLC)

Synonym(s):

1,5-Anhydro-D-glucitol

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About This Item

Empirical Formula (Hill Notation):
C6H12O5
CAS Number:
154-58-5
Molecular Weight:
164.16
EC Number:
205-829-3
MDL number:
MFCD00067386
UNSPSC Code:
12352201
PubChem Substance ID:
24891181
NACRES:
NA.25

Quality Level

200

assay

≥98.0% (TLC)

form

crystalline

color

white

solubility

water: 49.00-51.00 mg/mL, clear, colorless

SMILES string

OCC1OCC(O)C(O)C1O

InChI

1S/C6H12O5/c7-1-4-6(10)5(9)3(8)2-11-4/h3-10H,1-2H2

InChI key

MPCAJMNYNOGXPB-UHFFFAOYSA-N

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Application

1,5-Anhydro-D-sorbitol, a cyclic polyol, is a metabolic product of 1,5 anhydro-D-fructose. 1,5-Anhydro-D-sorbitol is used as a reference in analytical procedures that assess the metabolism of 1,5 anhydro-D-fructose, a food supplement with potential benefits as an antioxidant, antimicrobial, and antidiabetic agent.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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David C Klonoff et al.
Diabetes, obesity & metabolism (2018-12-12)
To evaluate the efficacy and safety of fast-acting insulin aspart (faster aspart) vs insulin aspart (IAsp) used in continuous subcutaneous insulin infusion (CSII) in participants with type 1 diabetes (T1D). This was a double-blind, treat-to-target, randomized, 16-week trial investigating CSII
Sanjeev N Mehta et al.
Pediatric diabetes, 13(3), 278-284 (2011-11-09)
Serum 1,5-anhydroglucitol (1,5-AG) is a marker of hyperglycemic excursions in adults with diabetes and hemoglobin A1c (HbA1c) < 8%. We compared 1,5-AG levels among youth and young adults with and without type 1 diabetes (T1D) and investigated the utility of
Stephen P Juraschek et al.
Diabetes care, 35(11), 2265-2270 (2012-08-10)
Fructosamine, glycated albumin, and 1,5-anhydroglucitol (1,5-AG) are of interest for monitoring short-term glycemic control in patients with diabetes; however, their associations with diabetes risk are uncharacterized. We used Cox proportional hazards models to examine the associations of fructosamine, glycated albumin
Andrzej S Januszewski et al.
Diabetes research and clinical practice, 95(1), e17-e19 (2011-10-26)
An assay of plasma 1,5-anhydroglucitol was evaluated. Assay CVs, effects of four plasma freeze-thaw cycles, glucose up to 80 mmol/L and triglycerides up to 20 mmol/L were acceptable. 1,5-anhydroglucitol levels were significantly lower in diabetic vs. non-diabetic subjects and correlated
Won Jun Kim et al.
Diabetes care, 35(2), 281-286 (2012-01-03)
To assess the relationship between 1,5-anhydroglucitol (AG) levels, which are a marker of glycemic control, and stages of chronic kidney disease (CKD). This was a cross-sectional study with 269 subjects with type 2 diabetes who were divided into four groups
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