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A2628

Sigma-Aldrich

L-Alanine β-naphthylamide

protease substrate

Synonym(s):

L-Alanine 2-naphthylamide

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1 G
$174.00

$174.00

Available to ship onApril 08, 2025Details

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1 G
$174.00

About This Item

Empirical Formula (Hill Notation):
C13H14N2O
CAS Number:
720-82-1
Molecular Weight:
214.26
EC Number:
211-956-5
MDL number:
MFCD00064969
UNSPSC Code:
12352204
eCl@ss:
32160406
PubChem Substance ID:
24890677
NACRES:
NA.83

$174.00

Available to ship onApril 08, 2025Details

assay

≥98% (TLC)

form

powder

solubility

ethanol: 50 mg/mL, clear to slightly hazy

storage temp.

2-8°C

SMILES string

C[C@H](N)C(=O)Nc1ccc2ccccc2c1

InChI

1S/C13H14N2O/c1-9(14)13(16)15-12-7-6-10-4-2-3-5-11(10)8-12/h2-9H,14H2,1H3,(H,15,16)/t9-/m0/s1

InChI key

RQHPADKWNYTHOH-VIFPVBQESA-N

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Application

L-Alanine Ǧ-naphthylamide has been used to determine the activity of alanine aminopeptidase (AAP) in blood samples.[1] It may be used as a fluorescent substrate to assay neutral aminopeptidase (APN) activity in cultured human and mouse chondrocytes.[2][3]

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM0893
BCCL2076
BCCJ7819
BCCF8751
BCCF0430

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Anna Bizoń et al.
Environmental toxicology and pharmacology, 53, 74-80 (2017-05-16)
The effect of tobacco smoke on lipid peroxidation, the lipid profile and membrane-bound enzymatic activity in the first trimester of pregnancy was investigated. In the plasma of women with active exposure to tobacco smoke, we have found increased lipid peroxidation
Simone Cristina Yamasaki et al.
Regulatory peptides, 173(1-3), 47-54 (2011-10-11)
This study evaluated the hypothesis that neutral (APN) and dipeptidyl-IV (DPPIV) aminopeptidase activity levels would be critical for the susceptibility to arthritis in collagen-induced model (CIA). The macroscopic signs of arthritis in CIA rats were checked and peripheral blood, synovial
D R Buckler et al.
Biochemistry, 34(49), 15965-15978 (1995-12-12)
Formation of local structure and overall chain dimensions in the 124-residue, four-disulfide protein bovine pancreatic ribonuclease A (RNase A) under conditions favoring either the native or partially folded states have been studied by nonradiative excitation energy transfer measurements. Three RNase
Meriam Nefla et al.
Journal of cell science, 128(17), 3250-3262 (2015-07-26)
Osteoarthritis is a whole-joint disease characterized by the progressive destruction of articular cartilage involving abnormal communication between subchondral bone and cartilage. Our team previously identified 14-3-3ε protein as a subchondral bone soluble mediator altering cartilage homeostasis. The aim of this
C I Cheeseman et al.
Canadian journal of physiology and pharmacology, 60(9), 1177-1184 (1982-09-01)
The uptake of the peptide glycyl-L-leucine across the brush border of the rat small intestinal enterocyte was studied using everted rings. The transfer of leucine from the dipeptide into the enterocyte was greater than the glycine uptake from glycyl-L-leucine. This
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