A0851

Anti-Angiopoietin-2 antibody produced in goat

affinity isolated antibody, lyophilized powder

• Synonym(s): Anti-Ang-2
• UNSPSC Code: 51111800
• NACRES: NA.41
• MDL number: MFCD03096608
• Conjugate: unconjugated
• Clone: polyclonal
• Application: ELISA, IHC (p), WB
• Citations: 3

Properties

• biological source: goat
• Quality Segment: 100
• recombinant: expressed in goat
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• mol wt: antigen ~66 kDa
• species reactivity: human
• technique(s): ELISA: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): 5-15 μg/mL using human tissue, western blot: 0.1-0.2 μg/mL
• UniProt accession no.: O15123
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... ANGPT2(285)

Description

General description

Angiopoietin 2 is an endothelial cell-specific protein and has a pivotal role in mature blood vessel formation, endothelial cell proliferation and embryogenic angiogenesis. Angiopoietin 2 produced by endothelial cells of interior tumor vessels, stimulates vessel regression and disassociation from surrounding tumor cells. Anti-angiopoietin-2 antibody can be used in western blotting. Goat anti-angiopoietin-2 antibody reacts specifically with recombinant human angiopoietin-2. The product may also show 25% (approx.) cross-reactivity for recombinant human angiopoietin-1.

Immunogen

purified recombinant human angiopoietin-2 expressed in mouse NSO cells.

Application

Anti-angiopoietin-2 antibody can be used in immunohistochemistry for detecting humanangiopoietin-2 using paraffin-embedded human tissue sections. It can also be used in ELISA.

Goat anti-angiopoietin-2 antibody is also suitable for use in western blot assays at 0.1-0.2 μg/mL

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline (pH 7.4) with 5% trehalose

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): Eyeshields, Gloves, type N95 (US)