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A0851

Sigma-Aldrich

Anti-Angiopoietin-2 antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-Ang-2

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About This Item

MDL number:
MFCD03096608
UNSPSC Code:
51111800
NACRES:
NA.41

biological source

goat

Quality Level

100

recombinant

expressed in goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

mol wt

antigen ~66 kDa

species reactivity

human

technique(s)

ELISA: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 5-15 μg/mL using human tissue
western blot: 0.1-0.2 μg/mL

UniProt accession no.

O15123

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ANGPT2(285)

Related Categories

General description

Angiopoietin 2 is an endothelial cell-specific protein and has a pivotal role in mature blood vessel formation, endothelial cell proliferation and embryogenic angiogenesis. Angiopoietin 2 produced by endothelial cells of interior tumor vessels, stimulates vessel regression and disassociation from surrounding tumor cells. Anti-angiopoietin-2 antibody can be used in western blotting. Goat anti-angiopoietin-2 antibody reacts specifically with recombinant human angiopoietin-2. The product may also show 25% (approx.) cross-reactivity for recombinant human angiopoietin-1.

Immunogen

purified recombinant human angiopoietin-2 expressed in mouse NSO cells.

Application

Anti-angiopoietin-2 antibody can be used in immunohistochemistry for detecting humanangiopoietin-2 using paraffin-embedded human tissue sections. It can also be used in ELISA.
Goat anti-angiopoietin-2 antibody is also suitable for use in western blot assays at 0.1-0.2 μg/mL

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline (pH 7.4) with 5% trehalose

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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