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A0451

Aloin

from Curacao aloe, ~50%

Synonym(s):

1,8-Dihydroxy-10-(β-D-glucopyranosyl)-3-(hydroxymethyl)-9(10H)-anthracenone, 10-β-D-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone, Aloin A, Barbaloin

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About This Item

Empirical Formula (Hill Notation):
C21H22O9
CAS Number:
1415-73-2
Molecular Weight:
418.39
UNSPSC Code:
41116107
NACRES:
NA.79
PubChem Substance ID:
24890427
EC Number:
215-808-0
Beilstein/REAXYS Number:
6077558
MDL number:
MFCD00151160

Key Documents

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biological source

Curacao aloe

Quality Level

100

form

powder

concentration

~50%

color

yellow to brown

mp

418.39  °C ((785.10 °F ))

solubility

pyridine: 50 mg/mL, clear, dark red to very dark red and red purple

storage temp.

room temp

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)[C@H]2c3cccc(O)c3C(=O)c4c(O)cc(CO)cc24

InChI

1S/C21H22O9/c22-6-8-4-10-14(21-20(29)19(28)17(26)13(7-23)30-21)9-2-1-3-11(24)15(9)18(27)16(10)12(25)5-8/h1-5,13-14,17,19-26,28-29H,6-7H2/t13-,14+,17-,19+,20-,21+/m1/s1

InChI key

AFHJQYHRLPMKHU-OSYMLPPYSA-N

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1 of 4

This Item
B6906PHL895581013727
Aloin from Curacao aloe, ~50%

Sigma-Aldrich

A0451

Aloin

Aloin from Aloe barbadensis Miller leaves, ≥97%

Sigma-Aldrich

B6906

Aloin

Aloin A phyproof® Reference Substance

PHL89558

Aloin A

Aloin United States Pharmacopeia (USP) Reference Standard

USP

1013727

Aloin

biological source

Curacao aloe

biological source

Aloe barbadensis Miller leaves

biological source

-

biological source

-

Quality Level

100

Quality Level

200

Quality Level

-

Quality Level

-

solubility

pyridine: 50 mg/mL, clear, dark red to very dark red and red purple

solubility

methanol: 100 mg/mL, clear to very slightly hazy, light yellow to yellow

solubility

-

solubility

-

form

powder

form

powder

form

-

form

-

storage temp.

room temp

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

mp

418.39  °C ((785.10 °F ))

mp

-

mp

-

mp

-

Biochem/physiol Actions

Purgative activity in rats requires activation by Eubacterium sp. strain BAR or similar intestinal anaerobe, presumably by conversion to aloe-emodin anthrone.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SLBC4749V
020M0053V
020M0053
090K1141
056H0487

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K Shimpo et al.
Phytotherapy research : PTR, 15(8), 705-711 (2001-12-18)
We examined the modifying effect of whole-leaf Aloe arborescens Miller var. natalensis Berger (designated as 'ALOE') on azoxymethane (AOM)-induced aberrant crypt foci (ACF), putative preneoplastic lesions, in the rat colorectum. Male F344 rats (4 weeks old) were fed the basal
Tetsuya Shindo et al.
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 43(3), 115-121 (2002-09-20)
Four kinds of barbaloin (BA)-related compounds (A, B, C, D) in aloe drinks were isolated by using preparative HPLC. LC/MS analyses of these compounds showed the identical quasimolecular ion peak at m/z 833 [M-H]-. The chemical structures were mainly determined
Evandro L Duarte et al.
Langmuir : the ACS journal of surfaces and colloids, 24(8), 4041-4049 (2008-03-06)
Barbaloin is a bioactive glycosilated 1,8-dihydroxyanthraquinone present in several exudates from plants, such as Aloe vera, which are used for cosmetic or food purposes. It has been shown that barbaloin interacts with DMPG (dimyristoylphosphatidylglycerol) model membranes, altering the bilayer structure
Metabolism of barbaloin by intestinal bacteria.
M Hattori et al.
Chemical & pharmaceutical bulletin, 36(11), 4462-4466 (1988-11-01)
Jin-dong Chen et al.
Se pu = Chinese journal of chromatography, 20(4), 367-368 (2003-01-25)
Barbaloin in aloe capsule was quantitatively determined by high performance liquid chromatography with ODS column, a mixture of CH3OH-H2O (50:50, volume ratio) as mobile phase and UV detection at 298 nm. There was a good linear relationship within the range
View All Related Papers

Global Trade Item Number

SKUGTIN
A0451-25G04061833333921

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