the machine aliquots 0.1ml per test. Therefore, ideally, 7mls would be sufficient for 70 tests. However, due to priming and testing, it is more realistic to expect about 60 to 65 tests when using it in a prep kit.
392M-1
Langerin (12D6) Mouse Monoclonal Antibody
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1 ML
$186.00
0.1 ML
$197.00
7 ML
$575.00
0.5 ML
$594.00
1 ML
$930.00
About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
12D6, monoclonal
Application:
IHC (p)
Citations:
1
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biological source
mouse
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
12D6, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (392M-14), vial of 0.5 mL concentrate (392M-15), bottle of 1.0 mL predilute (392M-17), vial of 1.0 mL concentrate (392M-16), bottle of 7.0 mL predilute (392M-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
isotype
IgG2bκ
control
Langerhans cell histiocytosis
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
Gene Information
human ... CD207(50489)
Related Categories
1 of 4
This Item | |||
|---|---|---|---|
| species reactivity human | species reactivity human | species reactivity human | species reactivity human |
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| antibody form culture supernatant | antibody form diluted ascites fluid | antibody form culture supernatant | antibody form ascites fluid |
| clone 12D6, monoclonal | clone L26, monoclonal | clone 6H6, monoclonal | clone LL002, monoclonal |
| biological source mouse | biological source mouse | biological source mouse | biological source mouse |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
General description
Langerin is a type II transmembrane C-type lectin associated with the formation of Birbeck granules in Langerhans cells. The demonstration of langerin immunoreactivity is considered an adjunct or alternative to CD1a antigen expression as evidence to aid in the diagnosis of Langerhans cell histiocytosis. Evaluation of langerin expression is valuable in circumstances where a diagnosis of Langerhans cell histiocytosis is suspected, but cannot be confirmed due to lack of CD1a immunoreactivity. A panel of antibodies against CD1a, langerin, CD21, CD23, CD35 and S100 is very useful in the distinction of Langerhans cell histiocytosis, histiocytic sarcoma, interdigitating dendritic cell sarcoma, follicular dendritic cell sarcoma, disseminated juvenile xanthogranuloma, and Rosai-Dorfman disease (sinus histiocytosis with massive lymphadenopathy).
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Analysis Note
 IVD |  IVD |  IVD |  RUO |
Other Notes
For Technical Service please contact: 800-665-7284 or email: [email protected]
Langerin Positive Control Slides, Product No. 392S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Sean K Lau et al.
The American journal of surgical pathology, 32(4), 615-619 (2008-02-19)
Langerin is a type II transmembrane C-type lectin associated with the formation of Birbeck granules in Langerhans cells. Langerin is a highly selective marker for Langerhans cells and the lesional cells of Langerhans cell histiocytosis. Although Langerin protein expression in
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 392M-14 | 0841683140528 |
| 392M-16 | 0841683140542 |
| 392M-15 | 0841683140535 |
| 392M-18 | 0841683140566 |
| 392M-17 | 0841683140559 |
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how many tests can one get out of a 7ml predilute of Laangerin 392M-18?
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