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296M-1

Sigma-Aldrich

Myogenin (F5D) Mouse Monoclonal Antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

F5D, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (296M-14)
vial of 0.5 mL concentrate (296M-15)
bottle of 1.0 mL predilute (296M-17)
vial of 1.0 mL concentrate (296M-16)
bottle of 7.0 mL predilute (296M-18)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

isotype

IgG1κ

control

rhabdomyosarcoma

shipped in

wet ice

storage temp.

2-8°C

visualization

nuclear

Gene Information

human ... MYOG(4656)

General description

Myogenin also identified as myogenic factor 4 is a muscle-specific transcription factorassociated with muscle differentiation and cell cycle. Anti-myogenin reactivity isseen in the nuclei of myoblasts in developing muscle tissue. Anti-myogenin is a usefulimmunohistochemical reagent for the identification of rhabdomyosarcoma.

Quality


IVD
IVD
IVD
RUO

Linkage

Myogenin Positive Control Slides, Product No. 296S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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S Cui et al.
Pathology international, 49(1), 62-68 (1999-05-05)
New monoclonal anti-MyoD1 and anti-myogenin antibodies were evaluated immunohistochemically to determine whether they are useful in discriminating rhabdomyosarcoma (RMS) from other soft tissue tumors in routinely processed sections. Neither MyoD1 nor myogenin was expressed in normal, mature striated muscle. In
J B Miller
The Journal of cell biology, 111(3), 1149-1159 (1990-09-01)
Different mouse muscle cell lines were found to express distinct patterns of myosin heavy chain (MHC) isoforms, MyoD1, and myogenin, but there appeared to be no correlation between the pattern of MHC expression and the patterns of MyoD1 and myogenin
N P Wang et al.
The American journal of pathology, 147(6), 1799-1810 (1995-12-01)
The distinction of rhabdomyosarcoma (RMS) from other small blue round cell tumors of childhood, such as Ewing's sarcoma/peripheral primitive neuroectodermal tumor (pPNET) and neuroblastoma, continues to present a diagnostic challenge to pathologists. The recent recognition of the master role of

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