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107689

Sigma-Aldrich

Hexadimethrine bromide

≥95%

Synonym(s):

1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide, Polybrene

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About This Item

CAS Number:
28728-55-4
MDL number:
MFCD00133397
UNSPSC Code:
41106502
NACRES:
NA.26

assay

≥95%

storage temp.

2-8°C

InChI

1S/C10H24N2.C3H6Br2/c1-11(2)9-7-5-6-8-10-12(3)4;4-2-1-3-5/h5-10H2,1-4H3;1-3H2

InChI key

KZKAYEGOIJEWQB-UHFFFAOYSA-N

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Application


  • Adaptive and Ultrahigh-Affinity Recognition in Water by Sulfated Conjugated Corral[5]arene.: Research on Hexadimethrine bromide′s interaction with sulfated corral[5]arene under aqueous conditions, exploring its high-affinity binding properties which could be crucial for developing new biochemical sensors (Wang et al., 2024).

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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G Montalescot et al.
Circulation, 82(5), 1754-1764 (1990-11-01)
Protamine reversal of heparin anticoagulation in patients is occasionally associated with life-threatening acute pulmonary hypertension. In a sheep model, we evaluated the effect on this adverse cardiopulmonary reaction of modifying the type of heparin (low molecular weight heparin compared with
Noam Auslander et al.
Molecular systems biology, 13(12), 956-956 (2017-12-03)
Metabolic alterations play an important role in cancer and yet, few metabolic cancer driver genes are known. Here we perform a combined genomic and metabolic modeling analysis searching for metabolic drivers of colorectal cancer. Our analysis predicts FUT9, which catalyzes
Yujie Zhang et al.
Scientific reports, 7, 41173-41173 (2017-01-24)
Excessive deposition of type I collagen causes fibrotic diseases. Binding of La ribonucleoprotein domain family, member 6 (LARP6) to collagen mRNAs regulates their translation and is necessary for high type I collagen expression. Here we show that mTORC1 phosphorylates LARP6
Abdulrahman Jama et al.
The Journal of physiology, 597(3), 889-901 (2018-12-05)
Lipin1 is critical for skeletal muscle development. Lipin1 regulates MyoD and myocyte-specific enhancer factor 2C (MEF2c) expression via the protein kinase C (PKC)/histone deacetylase 5-mediated pathway. Inhibition of PKCμ activity suppresses myoblast differentiation by inhibiting MyoD and MEF2c expression. Our
Yuji Kondo et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(12), 4714-4719 (2013-03-09)
Although endogenous ligands for Toll-like receptor (TLR)4-myeloid differentiation factor 2 (MD2) have not been well-understood, we here report that a globo-series glycosphingolipid, globotetraosylceramide (Gb4), attenuates the toxicity of lipopolysaccharides (LPSs) by binding to TLR4-MD-2. Because α1,4-galactosyltransferase (A4galt)-deficient mice lacking globo-series
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