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Key Documents

Y0000798

Pholcodine for peak identification

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Pholcodine

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About This Item

Empirical Formula (Hill Notation):
C23H30N2O4
CAS Number:
509-67-1
Molecular Weight:
398.50
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

pholcodine

manufacturer/tradename

EDQM

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C23H30N2O4/c1-24-7-6-23-16-3-4-18(26)22(23)29-21-19(5-2-15(20(21)23)14-17(16)24)28-13-10-25-8-11-27-12-9-25/h2-5,16-18,22,26H,6-14H2,1H3/t16?,17-,18+,22+,23+/m1/s1

InChI key

GPFAJKDEDBRFOS-SLITUTQKSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Pholcodine for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Lot/Batch Number

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IgE-mediated anaphylactic reactions to neuromuscular blocking agents: can they be prevented?
E Florvaag et al.
Current allergy and asthma reports, 8(5), 375-376 (2008-08-07)
Allergy to pholcodine: first case documented by oral challenge.
F Codreanu et al.
Allergy, 60(4), 544-545 (2005-02-25)
Didier G Ebo et al.
Anesthesiology, 107(2), 253-259 (2007-08-02)
Diagnosis of allergy from neuromuscular blocking agents is not always straightforward. The objectives of the current study were to investigate the value of quantification of immunoglobulin E (IgE) by ImmunoCAP (Phadia AB, Uppsala, Sweden) in the diagnosis of rocuronium allergy
E Florvaag et al.
Allergy, 61(1), 49-55 (2005-12-21)
A previous study showed a relation between pholcodine (PHO) consumption, prevalence of IgE-sensitization to PHO, morphine (MOR) and suxamethonium (SUX) and anaphylaxis to neuromuscular blocking agents (NMBA). The purpose of this pilot study was to explore the effect on IgE
Pholcodine caused anaphylaxis in Sweden 30 years ago.
S G O Johansson et al.
Allergy, 64(5), 820-821 (2009-02-13)
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