150495

Isopentyl nitrite

96%

• Synonym(s): Isoamyl nitrite
• Linear Formula: (CH₃)₂CHCH₂CH₂ONO
• CAS Number: 110-46-3
• Molecular Weight: 117.15
• Beilstein/REAXYS Number: 969510
• EC Number: 203-770-8
• MDL number: MFCD00002057
• UNSPSC Code: 12171500
• PubChem Substance ID: 24849038
• NACRES: NA.47

Properties

• Quality Level: 200
• assay: 96%
• form: liquid
• color: colorless to green-yellow; colorless to yellow
• refractive index: n20/D 1.386 (lit.)
• bp: 99 °C (lit.)
• mp: <-80 °C
• solubility: water: soluble 0.38 g/L at 25 °C
• density: 0.872 g/mL at 25 °C (lit.)
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: 2-8°C
• SMILES string: CC(C)CCON=O
• InChI: 1S/C5H11NO2/c1-5(2)3-4-8-6-7/h5H,3-4H2,1-2H3
• InChI key: OWFXIOWLTKNBAP-UHFFFAOYSA-N

Description

General description

Isopentyl nitrite, also known as isoamyl nitrite, is an oxidant, and nitrosating agent for phosphoramidites which rearrange into phosphotriesters during nitrosation.

Application

Isopentyl nitrite has been used:

• as a radical initiator to functionalize multi-walled carbon nanotubes.
• as a reagent in the preparation of 4-carboxy-phenyl diazonium salt tetrafluoroborate.
• in the synthesis of peroxynitrite (ONOO-).

Isopentyl nitrite, also known as isoamyl nitrite, is used for the generation of benzyne from anthranilic acid. It is a smooth muscle relaxant that may be suitable as nitrovasodilators and as recreational drugs known as poppers. Its applications are also seen in kits to treat cyanide poisoning, its function being to oxidize hemoglobin (Hb) to methemoglobin (metHb) which reacts with cyanide to form the non-toxic cyano-metHb.

Safety Information

• pictograms: GHS02,GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H225,H302 + H332,H314,H317,H341
• pcodes: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: -4.0 °F - closed cup
• flash_point_c: -20 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter