Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

02191

Sigma-Aldrich

Adipic acid dihydrazide

purum, ≥97.0% (NT)

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
NH2NHCO(CH2)4CONHNH2
CAS Number:
1071-93-8
Molecular Weight:
174.20
Beilstein/REAXYS Number:
973863
EC Number:
213-999-5
MDL number:
MFCD00007614
UNSPSC Code:
12352200
PubChem Substance ID:
329747401

grade

purum

assay

≥97.0% (NT)

mp

180-182 °C (lit.)
180-182 °C

SMILES string

NNC(=O)CCCCC(=O)NN

InChI

1S/C6H14N4O2/c7-9-5(11)3-1-2-4-6(12)10-8/h1-4,7-8H2,(H,9,11)(H,10,12)

InChI key

IBVAQQYNSHJXBV-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Adipic acid dihydrazide can be used to study chemical synthesis, organic building blocks, carbonyl compounds and hydrazides. Adipic acid dihydrazide has been used in a study to show that diphtheria toxoid can be successfully employed as a carrier protein for conjugation with Salmonella O-specific polysaccharides and play an important role in facilitating adequate immune response in typhoid fever vaccines. Adipic acid dihydrazide has also been used in a study to assess the activity of the derivatives of glycoside steviolbioside from the plant Stevia rebaudiana.

Other Notes

Bifunctional linker employed for the immobilization of carbohydrates, e.g. to MMAC resins (methyl vinyl ether, maleic anhydride co-polymer)[1][2]

replaced by

Product No.
Description
Pricing

pictograms

Environment
GHS09

hcodes

H411

Hazard Classifications

Aquatic Chronic 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

302.0 °F - closed cup

flash_point_c

150 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A Satoh et al.
Analytical biochemistry, 275(2), 231-235 (1999-12-20)
The immobilization of carbohydrates for solid-phase assays, including enzyme-linked immunosorbent assay (ELISA), is difficult because they are hydrophilic. We developed four new methods for the immobilization of oligosaccharides. ELISA plates were first coated with methyl vinyl ether-maleic anhydride copolymer (MMAC)
A Satoh et al.
Analytical biochemistry, 260(1), 96-102 (1998-07-02)
We have previously reported a method to immobilize protein ligands on microtiter plates coated with methyl vinyl ether-maleic anhydride copolymer (MMAC) [Isosaki, K., et al. (1992) J. Chromatogr. 597, 123-128]. In this study, we improved the MMAC method to efficiently
Tulsidas G Shrivastav
Journal of immunoassay & immunochemistry, 25(3), 295-304 (2004-10-06)
Peroxidase hydrazides were prepared by conjugating horseradish peroxidase (HRP) to adipic acid dihydrazide (ADH) by carbodiimide or periodate oxidation method. The resulting HRP hydrazides (ADH-HRP) were conjugated to cortisol-21-hemisuccinate (cortisol-21-HS) by forming diimide bonds using the N-hydroxysuccinimide (NHS) carbodiimide mediated
Yu-Chun Chen et al.
Acta biomaterialia, 9(2), 5181-5193 (2012-10-09)
Encapsulation of nucleus pulposus (NP) cells within in situ forming hydrogels is a novel biological treatment for early stage intervertebral disc degeneration. The procedure aims to prolong the life of the degenerating discs and to regenerate damaged tissue. In this
So Jung An et al.
Vaccine, 29(44), 7618-7623 (2011-08-17)
In this study it was demonstrated that the immunogenicity of Vi polysaccharide-diphtheria toxoid conjugates was related to the physical and chemical structure of the conjugate. Conjugates were prepared in two steps, firstly binding adipic acid dihydrazide (ADH) spacer molecules to
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service