SCC209
Caco-2/TC-7 Human Colon Adenocarcinoma Cell Line
Synonym(s):
Caco-2/TC-7 Human Colon Adenocarcinoma Cell Line
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About This Item
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packaging
pkg of >1X10⁶ vials
manufacturer/tradename
Sigma-Aldrich
growth mode
N/A
technique(s)
cell culture | mammalian: suitable
shipped in
dry ice
storage temp.
≤ − 140°C
Application
Caco-2/TC-7 Human Colon Adenocarcinoma Cell Line was isolated from a late passage of the parental Caco-2 cell line and comprises a more homogeneus population of cells that exhibit the characteristic functions of small intestinal enterocytes including organization of the apical brush border, distribution of the associated hydrolase sucrase-isomaltase (SI), more developed interceliular tight junctions and a shorter differentiation time (1).Reference:1. J. Cell Sci. 1994; 107(Pt 1): 213-225
• Each vial contains ≥ 1X10⁶ viable cells.• Cells are tested negative for infectious diseases by a Human Essential CLEAR panel by Charles River Animal Diagnostic Services.• Cells are verified to be of human origin and negative for inter-species contamination from rat, mouse, chinese hamster, Golden Syrian hamster, and non-human primate (NHP) as assessed by a Contamination CLEAR panel by Charles River Animal Diagnostic Services.• Cells are negative for mycoplasma contamination.• Each lot of cells is genotyped by STR analysis to verify the unique identity of the cell line.
Features and Benefits
Caco-2/TC-7 human colon adenocarcinoma cell line is a useful model for intestinal drug permeability and absorption studies.
Storage and Stability
Store in liquid nitrogen. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.
Other Notes
This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation.
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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