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Key Documents

MAB5552

Sigma-Aldrich

Anti-Pax6 Antibody

ascites fluid, clone AD2.38, Chemicon®

Synonym(s):

Anti-AN, Anti-AN2, Anti-ASGD5, Anti-D11S812E, Anti-FVH1, Anti-MGDA, Anti-WAGR

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

antibody form

ascites fluid

antibody product type

primary antibodies

clone

AD2.38, monoclonal

species reactivity

rat, chicken, mouse, human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable (paraffin)
western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... PAX6(5080)

Specificity

Recognizes Pax6. The antibody recognizes both products of the two major alternatively spliced forms.

Immunogen

Recombinant human Pax6.

Application

Detect Pax6 using this Anti-Pax6 Antibody validated for use in IH(P) & WB.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience

Neuronal & Glial Markers
Western blot. The antibody recognizes the 46 and 48 kDa Pax6 proteins.

Immunohistochemistry on paraffin embedded tissue sections.

Optimal working dilutions must be determined by end user.

Target description

46 & 48 kDa

Physical form

Ascites fluid containing no preservatives.
Unpurified

Storage and Stability

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
Embryonic eye tissue

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
This product can not be purchased for resale.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mercedes Mirasierra et al.
Diabetologia, 59(4), 766-775 (2016-01-08)
The stimulation of glucagon secretion in response to decreased glucose levels has been studied extensively. In contrast, little is known about the regulation of glucagon gene expression in response to fluctuations in glucose concentration. Paired box 6 (PAX6) is a
Evgeniya V Pushchina et al.
Neural regeneration research, 8(1), 13-23 (2013-01-05)
We investigated the distribution of gamma aminobutyric acid, tyrosine hydroxylase and nitric oxide-producing elements in a cherry salmon Oncorhynchus masou brain at various stages of postnatal ontogenesis by immunohistochemical staining and histochemical staining. The periventricular region cells exhibited the morphology
Susanna Croci et al.
European journal of human genetics : EJHG, 28(10), 1446-1458 (2020-06-17)
Variations in the Forkhead Box G1 (FOXG1) gene cause FOXG1 syndrome spectrum, including the congenital variant of Rett syndrome, characterized by early onset of regression, Rett-like and jerky movements, and cortical visual impairment. Due to the largely unknown pathophysiological mechanisms
Fabio Michelet et al.
Stem cell research & therapy, 11(1), 47-47 (2020-02-06)
Despite increasing demand, current protocols for human pluripotent stem cell (hPSC)-derived retinal pigment epithelium (RPE) remain time, labor, and cost intensive. Additionally, absence of robust methods for selective RPE purification and removal of non-RPE cell impurities prevents upscaling of clinical
Wen-Chung Liu et al.
International journal of environmental research and public health, 17(11) (2020-06-05)
Maternal high-fructose diets (HFD) impair the learning and memory capacity of adult female offspring via histone deacetylase 4 (HDAC4). Hippocampal adult neurogenesis is important for supporting the function of existing neural circuits. In this study, we investigated the effects of

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