14-334-M
PRAK Protein, active, 15 µg
Active, N-terminal His6-tagged recombinant, human, full-length PRAK, for use in Kinase Assays.
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About This Item
UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.32
biological source
human
Quality Level
100
300
recombinant
expressed in baculovirus infected Sf21 cells
mol wt
Mw 55 kDa
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
NCBI accession no.
UniProt accession no.
General description
N-terminal His6-tagged recombinant, human, full-length PRAK
Product Source: expressed by baculovirus in Sf21 insect cells
Biochem/physiol Actions
Protein Target: PRAK
Target Sub-Family: CAMK
Packaging
Also available in 250μg size (2x125μg) - Call for pricing and availability. Please reference catalog number 14-334M when ordering the 250μg size.
Quality
routinely evaluated by phosphorylation of PRAK Substrate Peptide
Physical form
Ni2+/NTA-agarose
Storage and Stability
6 months at -70C
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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L New et al.
The EMBO journal, 17(12), 3372-3384 (1998-06-17)
We have identified and cloned a novel serine/ threonine kinase, p38-regulated/activated protein kinase (PRAK). PRAK is a 471 amino acid protein with 20-30% sequence identity to the known MAP kinase-regulated protein kinases RSK1/2/3, MNK1/2 and MAPKAP-K2/3. PRAK was found to
S P Davies et al.
The Biochemical journal, 351(Pt 1), 95-105 (2000-09-22)
The specificities of 28 commercially available compounds reported to be relatively selective inhibitors of particular serine/threonine-specific protein kinases have been examined against a large panel of protein kinases. The compounds KT 5720, Rottlerin and quercetin were found to inhibit many
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