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05-764

Anti-MLL/HRX Antibody, NT., clone N4.4

clone N4.4, Upstate®, from mouse

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Size/SKUAvailabilityPrice
200 μg
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$700.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
N4.4, monoclonal
Application:
IP, WB
Citations:
24

$700.00


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biological source

mouse

Quality Segment

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

N4.4, monoclonal

species reactivity

mouse, human

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... KMT2A(4297)

General description

The acute lymphoblastic leukaemia (ALL)-1 (also known as MLL, HRX, HTRX, and TRX1) gene on human chromosome 11q23 is the site of many locally clustered chromosomal alterations associated with several types of acute leukaemias, including deletions, partial duplications and translocations. Structurally variant proteins derived from the altered gene presumably cause the malignant transformation of early haemopoietic progenitor cells.
300 kDa

Immunogen

MBP fusion protein corresponding to residues 161-356 of human mixed lineage leukemia, MLL

Application

Detect MLL/HRX with Anti-MLL/HRX Antibody, N-term., clone N4.4 (Mouse Monoclonal Antibody), that has been shown to work in IP & WB.

Biochem/physiol Actions

Recognizes N-terminal proteolytic fragment of MLL (MLLN).

Physical form

Format: Purified
Immunoaffinity Purified immunoglobulin in 0.014M phosphate buffer, pH 7.6, 0.175M NaCl, 0.07% sodium azide, and 30% glycerol.

Analysis Note

routinely evaluated by immunoblot on nuclear extract from K562 cells

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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species reactivity

mouse, human

species reactivity

mouse, human

species reactivity

human

species reactivity

human

clone

N4.4, monoclonal

clone

9-12, monoclonal

clone

polyclonal

clone

2E1, monoclonal

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

affinity purified immunoglobulin

antibody form

purified immunoglobulin

biological source

mouse

biological source

mouse

biological source

rabbit

biological source

mouse

Gene Information

human ... KMT2A(4297)

Gene Information

human ... KMT2A(4297)

Gene Information

rabbit ... MLL1(4297)

Gene Information

human ... MLL2(8085)


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Storage Class

10 - Combustible liquids

wgk

WGK 1



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