04-046

Anti-SUZ12 Antibody, clone 3C1.2

clone 3C1.2, Upstate^®, from mouse

• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: 3C1.2, monoclonal
• Application: WB
• Citations: 18

Properties

• Quality Segment: 100
• biological source: mouse
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 3C1.2, monoclonal
• species reactivity: human
• manufacturer/tradename: Upstate^®
• technique(s): western blot: suitable
• isotype: IgG1κ
• NCBI accession no.: NM_015355.1
• UniProt accession no.: Q15022
• shipped in: dry ice
• target post-translational modification: unmodified
• Gene Information: human ... SUZ12(23512)

Description

General description

95 kDa

SUZ12 is a polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility. Component of the PRC2 complex, which methylates ′Lys-9′ and ′Lys-27′ residues of histone H3.

Immunogen

Full length, recombinant human SUZ12.

Application

Anti-SUZ12 Antibody, clone 3C1.2 is a high quality Mouse Monoclonal Antibody for the detection of SUZ12 & has been validated in WB.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Chromatin Biology

Biochem/physiol Actions

SUZ12

Physical form

100 μg of Protein A purified mouse monoclonal IgG1κ in 100 μL of 1X PBS, pH 7, 0.1% Azide.

Format: Purified

Protein A purified

Preparation Note

2 years at -20°C from date of shipment.

Analysis Note

Control
HeLa cell lysate

Routinely evaluated by immunoblot.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable