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C108057

Sigma-Aldrich

N-Cyclohexyl-1,3-propanediamine

99%

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About This Item

Linear Formula:
C6H11NH(CH2)3NH2
CAS Number:
3312-60-5
Molecular Weight:
156.27
EC Number:
222-001-7
MDL number:
MFCD00003838
UNSPSC Code:
12352100
PubChem Substance ID:
24892337

assay

99%

form

liquid

refractive index

n20/D 1.482 (lit.)

bp

120-123 °C/20 mmHg (lit.)

mp

−17-−15 °C (lit.)

density

0.917 g/mL at 25 °C (lit.)

SMILES string

NCCCNC1CCCCC1

InChI

1S/C9H20N2/c10-7-4-8-11-9-5-2-1-3-6-9/h9,11H,1-8,10H2

InChI key

ITZPOSYADVYECJ-UHFFFAOYSA-N

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 1

flash_point_f

213.8 °F - closed cup

flash_point_c

101 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Certificates of Analysis (COA)

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M Huber et al.
Cancer research, 55(4), 934-943 (1995-02-15)
Spermine is often the most abundant polyamine in human tumors such as breast carcinomas. However, its specific role in tumor biology is still uncertain, since inhibitors of ornithine decarboxylase such as alpha-difluoromethylornithine depress cell growth while leaving spermine content mostly
P J Chu et al.
European journal of pharmacology, 256(2), 155-160 (1994-04-21)
The facilitating or antagonizing effects of polyamine analogues on N-methyl-DL-aspartate (NMDLA)-induced seizures were investigated using mice. Intracerebroventricular injection of spermidine and spermine, but not putrescine, shortened the latency to appearance of clonic convulsion induced by subcutaneous administration of NMDLA. Injection
Weiping Liu et al.
Chemical & pharmaceutical bulletin, 56(5), 659-662 (2008-05-03)
New JM118 (active form of satraplatin) analogues with N-cyclohexyl-1,3-propanediamine (N-chpda) as the carrier, cis-[Pt(N-chpda)X2] (X2=2Cl(-) (1), oxalate (2), malonate (3), 1,1-cyclobutanedicarboxylate (CBDCA) (3), and 3-hydroxy-1,1-cyclobutanedicarboxylate(HO-CBDCA) (4)), have been synthesized and characterized by elemental analysis and spectroscopic data along with X-ray
Masahiro Ohtani et al.
Cell structure and function, 34(2), 105-113 (2009-10-31)
In order to assess the functional role of the polyamines spermidine and spermine in pancreatic beta-cells, we examined the effect of spermidine and spermine synthase inhibitors, trans-4-methylcyclohexylamine (MCHA) and N-(3-aminopropyl)cyclohexylamine (APCHA), on cellular polyamine and insulin contents, insulin secretion, and
Kazuhiro Nishimura et al.
The Biochemical journal, 385(Pt 3), 779-785 (2004-09-21)
To examine the roles of active hypusinated eIF5A (eukaryotic translation initiation factor 5A) and polyamines in cell proliferation, mouse mammary carcinoma FM3A cells were treated with an inhibitor of deoxyhypusine synthase, GC7 (N1-guanyl-1, 7-diaminoheptane), or with an inhibitor of ornithine
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