900761

Sodium 4-methylpyridine-2-sulfinate

≥95%

• Synonym(s): Willis 4-methyl pyridine-2-sulfinate
• Empirical Formula (Hill Notation): C₆H₆NNaO₂S
• Molecular Weight: 179.17
• UNSPSC Code: 12352200

Properties

• assay: ≥95%
• form: powder or crystals
• reaction suitability: reaction type: C-C Bond Formation
• mp: 342 °C

Description

Application

This 2-pyridylsulfinate enables Suzuki-Miyaura cross coupling with aryl halides to access diverse pyridine derivatives as reported by the laboratory of Michael Willis.. No longer impeded by unstable 2-pyridyl boronates, the sulfinate alternatives provide Pd-catalyzed coupling routes to therapeutically valuable pyridine rings.

Other Notes

• Technology Spotlight: Willis Pyridinates for Palladium-Catalyzed Cross-Coupling Reactions.
• Pyridine Sulfinates as General Nucleophilic Coupling Partners in Palladium-Catalyzed Cross-Coupling Reactions with Aryl Halides

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable