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286486

Sigma-Aldrich

Dodecanoic anhydride

≥98%

Synonym(s):

Lauric anhydride

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About This Item

Linear Formula:
[CH3(CH2)10CO]2O
CAS Number:
645-66-9
Molecular Weight:
382.62
EC Number:
211-449-9
MDL number:
MFCD00008965
UNSPSC Code:
12352100
PubChem Substance ID:
24857242

assay

≥98%

form

crystals

mp

41-43 °C (lit.)

SMILES string

CCCCCCCCCCCC(=O)OC(=O)CCCCCCCCCCC

InChI

1S/C24H46O3/c1-3-5-7-9-11-13-15-17-19-21-23(25)27-24(26)22-20-18-16-14-12-10-8-6-4-2/h3-22H2,1-2H3

InChI key

NWADXBLMWHFGGU-UHFFFAOYSA-N

Gene Information

human ... FNTA(2339) , PGGT1B(5229)

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General description

The immunogenecity of the material made by coupling dodecanoic anhydride to NH2 groups was studied.

Application

Dodecanoic anhydride was used to chemically conjugate tumor cell membrane in carbonate buffer.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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S B Singh et al.
Journal of immunology (Baltimore, Md. : 1950), 120(3), 734-738 (1978-03-01)
A lipid conjugate of BSA was made by coupling dodecylamine to the COOH groups of BSA (DA-BSA). Studies on the immunogenicity of this material and one made by coupling dodecanoic anhydride to NH2 groups (D-BSA) demonstrated that cell-mediated immunity could
Petra Šedová et al.
Carbohydrate polymers, 216, 63-71 (2019-05-03)
The effect of hydrazide linkers on the formation and mechanical properties of hyaluronan hydrogels was intensively evaluated. The reaction kinetics of hydrazone formation was monitored by NMR spectroscopy under physiological conditions where polyaldehyde hyaluronan (unsaturated: ΔHA-CHO, saturated: HA-CHO) was reacted
R L Hunter et al.
Journal of the National Cancer Institute, 54(5), 1157-1163 (1975-05-01)
The covalent conjugation of fatty acid to a tumor cell membrane preparation transformed it from an antigen that enhanced tumor growth to one that suppressed it. A crude cell membrane preparation was made by sequential hypertonic and hypotonic salt extraction
Gordon D Sproul
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 49(4), 241-254 (2019-12-29)
Amino acids and peptides have been demonstrated to form lipoamino acids and lipopeptides under presumed prebiotic conditions, and readily form liposomes. Of the common nucleobases, adenine forms a liponucleobase even below 100 °C. Adenine as well as other nucleobases can also
C Bastiancich et al.
Journal of controlled release : official journal of the Controlled Release Society, 225, 283-293 (2016-02-02)
The local delivery of chemotherapeutic agents is a very promising strategy for the treatment of glioblastoma (GBM). Gemcitabine is a chemotherapeutic agent that has a different mechanism of action compared to alkylating agents and shows excellent radio-sensitizing properties. So, we
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