259063

(Methoxycarbonylmethyl)triphenylphosphonium bromide

98%

• Synonym(s): (Carbomethoxymethyl)triphenylphosphonium bromide, NSC 136109
• Linear Formula: CH₃OCOCH₂P(Br)(C₆H₅)₃
• CAS Number: 1779-58-4
• Molecular Weight: 415.26
• Beilstein/REAXYS Number: 3812975
• EC Number: 217-222-0
• MDL number: MFCD00011801
• UNSPSC Code: 12352108
• PubChem Substance ID: 24855683
• NACRES: NA.22

Properties

• assay: 98%
• reaction suitability: reaction type: C-C Bond Formation
• mp: 165-170 °C (dec.) (lit.)
• SMILES string: [Br-].COC(=O)C[P+](c1ccccc1)(c2ccccc2)c3ccccc3
• InChI: 1S/C21H20O2P.BrH/c1-23-21(22)17-24(18-11-5-2-6-12-18,19-13-7-3-8-14-19)20-15-9-4-10-16-20;/h2-16H,17H2,1H3;1H/q+1;/p-1
• InChI key: VCWBQLMDSMSVRL-UHFFFAOYSA-M

Description

Application

Reactant for synthesis of:

• GSK-3 inhibitors using theWittig reaction
• Substituted furanones for antifungal and cytostatic activities
• Photochromic dithienylethene derivatives
• Gem-diiodoalkanes containing allylic alcohols
• Highly substituted cyclopentenes and brazilanes via Au-catalyzed deoxygenative Nazarov cyclization

Reactant for:

• Asymmetric hydrogenation of α,β-unsaturated ester-phosphonates
• Studies of thermal decomposition of phosphonium alkyl ester salts

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves