157937

Dimethyl 2-oxoheptylphosphonate

technical grade, 85%

• Synonym(s): (2-Oxoheptyl)phosphonic acid dimethyl ester, Dimethyl (hexanoylmethyl)phosphonate
• Linear Formula: CH₃(CH₂)₄COCH₂P(O)(OCH₃)₂
• CAS Number: 36969-89-8
• Molecular Weight: 222.22
• Beilstein/REAXYS Number: 1946305
• EC Number: 253-293-4
• MDL number: MFCD00009514
• UNSPSC Code: 12352108
• PubChem Substance ID: 24849710
• NACRES: NA.22

Properties

• grade: technical grade
• assay: 85%
• reaction suitability: reaction type: C-C Bond Formation
• refractive index: n20/D 1.444 (lit.)
• bp: 109 °C/0.4 mmHg (lit.)
• density: 1.07 g/mL at 25 °C (lit.)
• SMILES string: CCCCCC(=O)CP(=O)(OC)OC
• InChI: 1S/C9H19O4P/c1-4-5-6-7-9(10)8-14(11,12-2)13-3/h4-8H2,1-3H3
• InChI key: LQZCYXCHWNQBKX-UHFFFAOYSA-N

Description

Application

Reactant for:

• Beirut reaction for the preparation of phosphonylated quinoxaline dioxides
• Preparation of pyrrolomorphinan derivatives as κ opioid agonists via cyclocondensation, Vilsmeier-Haack formylation, Horner-Wadsworth-Emmons reaction, and Kocienski-modified Julia olefination from naltrexone methyl ether
• Synthesis of C-glycosides amphiphiles via solvent-free Horner-Wadsworth-Emmons reaction with unprotected sugars
• Preparation of specific inhibitors of endocannabinoid biosynthesis

A key intermediate in prostaglandin synthesis.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 230.0 °F - closed cup
• flash_point_c: 110 °C - closed cup
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)