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  • Hexafluoroacetone as protecting and activating reagent: site-selective functionalization of iminodiacetic acid.

Hexafluoroacetone as protecting and activating reagent: site-selective functionalization of iminodiacetic acid.

Amino acids (2004-11-19)
T Rühl, C Böttcher, L Hennig, K Burger
ABSTRACT

Hexafluoroacetone was applied as a bidentate protecting and activating agent for the syntheses of RGD-peptide mimetics starting from iminodiacetic acid in solution and on solid phase.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Hexafluoroacetone trihydrate, 98%