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  • A novel stereoselective one-pot conversion of alcohols into alkyl halides mediated by N,N'-diisopropylcarbodiimide.

A novel stereoselective one-pot conversion of alcohols into alkyl halides mediated by N,N'-diisopropylcarbodiimide.

Chemical communications (Cambridge, England) (2003-02-15)
Stefano Crosignani, Brice Nadal, Zhengning Li, Bruno Linclau
ABSTRACT

Alcohols can be converted in high yields to the corresponding alkyl halides in a one-pot procedure via the corresponding O-alkylisourea; very short reaction times are possible when microwave irradiation is used.

MATERIALS
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Brand
Product Description

Sigma-Aldrich
DIC, purum, ≥98.0% (GC)