P4761
Poly-L-glutamic acid sodium salt
mol wt 15,000-50,000
Synonym(s):
L-Glutamic acid homopolymer sodium salt
Sign Into View Organizational & Contract Pricing
All Photos(4)
About This Item
Recommended Products
form
powder
Quality Level
mol wt
15,000-50,000
color
white to off-white
application(s)
detection
storage temp.
−20°C
InChI
1S/C15H23N3O10/c16-7(1-4-10(19)20)13(25)17-8(2-5-11(21)22)14(26)18-9(15(27)28)3-6-12(23)24/h7-9H,1-6,16H2,(H,17,25)(H,18,26)(H,19,20)(H,21,22)(H,23,24)(H,27,28)/t7-,8-,9-/m0/s1
InChI key
BUZMZDDKFCSKOT-CIUDSAMLSA-N
Looking for similar products? Visit Product Comparison Guide
Application
- Effect of Micelle-Incorporated Cisplatin With Sizes Ranging From 8 to 40 nm for the Therapy of Lewis Lung Carcinoma.: This research explores the use of micelle-incorporated cisplatin nanoparticles for cancer therapy, highlighting the significance of particle size on therapeutic efficacy. Poly-ʟ-glutamic acid sodium salt is used to improve drug delivery and target specificity (Wang Z et al., 2021).
- Ternary Polypeptide Nanoparticles with Improved Encapsulation, Sustained Release, and Enhanced In Vitro Efficacy of Carfilzomib.: This paper describes the development of ternary polypeptide nanoparticles, including poly-ʟ-glutamic acid sodium salt, to enhance the encapsulation and release of carfilzomib, an anticancer drug. The study demonstrates improved drug efficacy and controlled release profiles (Agbana P et al., 2020).
- Polymeric Core-Shell Nanoparticles Prepared by Spontaneous Emulsification Solvent Evaporation and Functionalized by the Layer-by-Layer Method.: This research focuses on the preparation of polymeric core-shell nanoparticles using a spontaneous emulsification method. Poly-ʟ-glutamic acid sodium salt is used to functionalize these nanoparticles, which can be applied in drug delivery systems (Szczęch M et al., 2020).
- Co-administration of Combretastatin A4 Nanoparticles and Sorafenib for Systemic Therapy of Hepatocellular Carcinoma.: This study evaluates the combined use of combretastatin A4 nanoparticles and sorafenib for treating liver cancer. Poly-ʟ-glutamic acid sodium salt is employed to enhance the stability and delivery of these nanoparticles, showing promise in improving therapeutic outcomes (Wang Y et al., 2019).
Analysis Note
Molecular weight based on viscosity.
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Sylwia Berbeć et al.
The journal of physical chemistry. B, 122(50), 11895-11905 (2018-11-15)
Replacing water with dimethyl sulfoxide (DMSO) completely reshapes the free-energy landscapes of solvated proteins. In DMSO, a powerful hydrogen-bond (HB) acceptor, formation of HBs between backbone NH groups and solvent is favored over HBs involving protein's carbonyl groups. This entails
Dolev Rimmerman et al.
The journal of physical chemistry. B, 123(9), 2016-2021 (2019-02-15)
Many biomaterials can adapt to changes in the local biological environment (such as pH, temperature, or ionic composition) in order to regulate function or deliver a payload. Such adaptation to environmental perturbation is typically a hierarchical process that begins with
Cell Type Influences Local Delivery of Biomolecules from a Bioinspired Apatite Drug Delivery System.
Jumana Alhamdi et al.
Materials (Basel, Switzerland), 11(9) (2018-09-16)
Recently, the benefit of step-wise sequential delivery of fibroblast growth factor-2 (FGF-2) and bone morphogenetic protein-2 from a bioinspired apatite drug delivery system on mouse calvarial bone repair was demonstrated. The thicknesses of the nanostructured poly-l-Lysine/poly-l-Glutamic acid polyelectrolyte multilayer (PEM)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service