Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

860841P

Avanti

C18(2S-OH) Galactosyl(β) Ceramide

Avanti Research™ - A Croda Brand

Synonym(s):

D-galactosyl-β1-1′-N-[2′′(S)-hydroxystearoyl]-D-erythro-sphingosine

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C42H81NO9
CAS Number:
168395-96-8
Molecular Weight:
744.09
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 5 mg (860841P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC([C@@H](O)CCCCCCCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@H]([C@H]1CO)O

General description

C18(2S-OH) Galactosyl(β) Ceramide, also known as D-galactosyl-β1-1′-N-[2′′(S)-hydroxystearoyl]-D-erythro-sphingosine is a hexosylceramide. Galactosyl(β) Ceramide synthesis is catalyzed by the enzyme β-GalCer synthase (UGT8A).

Biochem/physiol Actions

Galactosyl(β) Ceramide acts as a globotriaosylceramide synthase substrate to produce galabiaosylceramide. Altered levels of this lipid is associated with the development of various diseases including malignancy, sphingolipidosis, diabetes and chronic kidney diseases.

Packaging

5 mL Amber Glass Screw Cap Vial (860841P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Johanna von Gerichten et al.
Journal of lipid research, 58(6), 1247-1258 (2017-04-05)
Mammals synthesize, cell-type specifically, the diastereomeric hexosylceramides, β-galactosylceramide (GalCer) and β-glucosylceramide (GlcCer), which are involved in several diseases, such as sphingolipidosis, diabetes, chronic kidney diseases, or cancer. In contrast, Bacteroides fragilis, a member of the human gut microbiome, and the

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service