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  • Phthalide derivatives with antifungal activities against the plant pathogens isolated from the liquid culture of Pestalotiopsis photiniae.

Phthalide derivatives with antifungal activities against the plant pathogens isolated from the liquid culture of Pestalotiopsis photiniae.

The Journal of antibiotics (2011-09-15)
Xiao-Long Yang, Su Zhang, Qiong-Bo Hu, Du-Qiang Luo, Yan Zhang
ABSTRAKT

Three new phthalide derivatives (1-3) named 5-(3'-methyl-2'-butenyl)-2-hydroxy-3-methoxy-4-methylbenzoic acid (1), 5-(3'-carboxyl-3'-methyl-2E-allyloxy)-3-methoxy-4-methylphthalide (2) and 5-(3',3'-dimethylallyloxy)-2-methoxycarbonyl-3-methoxy-4-methylbenzoic acid (3) together with six known phthalide derivatives named 5-(3',3'-dimethylallyloxy)-3-methoxy-4-methylphthalide (4), zinnimidine (5), 5-(3',3'-dimethylallyloxy)-3-methoxy-4-methylphthalide (6), 5-(3',3'-dimethylallyloxy)-3-methoxy-4-methylphthalic acid (7), zinniol anhydride (8) and porriolide (9) were isolated from the liquid culture of the plant endophytic fungus Pestalotiopsis photiniae isolated from the Chinese Podocarpaceae plant Podocarpus macrophyllus. Their structures were elucidated by extensive spectroscopic analysis. Compounds 1-9 displayed significant antifungal activities against three plant pathogens.

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Sigma-Aldrich
Phthalide, 98%