1131009

Cholecalciferol

United States Pharmacopeia (USP) Reference Standard

• Synonim(y): (+)-Vitamin D₃, 7-Dehydrocholesterol activated, Activated 7-dehydrocholesterol, Calciol
• Wzór empiryczny (zapis Hilla): C₂₇H₄₄O
• Numer CAS: 67-97-0
• Masa cząsteczkowa: 384.64
• Beilstein: 2339331
• Numer MDL: MFCD00078131
• Kod UNSPSC: 41116107
• Identyfikator substancji w PubChem: 329749357
• NACRES: NA.24

Właściwości

• klasa czystości: pharmaceutical primary standard
• rodzina API: cholecalciferol
• producent / nazwa handlowa: USP
• mp: 83-86 °C (lit.)
• Zastosowanie: pharmaceutical (small molecule)
• format: neat
• temp. przechowywania: −20°C
• ciąg SMILES: CC(C)CCC[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C
• InChI: 1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1
• Klucz InChI: QYSXJUFSXHHAJI-YRZJJWOYSA-N
• informacje o genach: human ... VDR(7421)

Opis

Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Zastosowanie

Cholecalciferol USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Cholecalciferol Solution
• Cholecalciferol Capsules
• Cholecalciferol Tablets
• Cholecalciferol Chewable Gels
• Calcium with Vitamin D Tablets
• Oil-Soluble Vitamins Preparation

Działania biochem./fizjol.

Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis.

Komentarz do analizy

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Inne uwagi

Sales restrictions may apply.

Informacja o środkach bezpieczeństwa

• Piktogramy: GHS06,GHS08
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H300 + H310 + H330,H372
• Zwroty wskazujące środki ostrożności: P260 - P262 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P314
• Klasyfikacja zagrożeń: Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - STOT RE 1 Oral
• Kod klasy składowania: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable