SML2573

MitoCDNB

≥98% (HPLC), mitochondrial thiol redox inactivator, powder

• Synonym(s): [4-(5’-Chloro-2’,4’-dinitrophenylamino)but-1-yl]triphenylphosphonium methanosulfonate
• Empirical Formula (Hill Notation): C₂₉H₂₉ClN₃O₇PS
• Molecular Weight: 630.05
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Product Name: MitoCDNB, ≥98% (HPLC)
• assay: ≥98% (HPLC)
• form: powder
• color: white to very dark brown
• solubility: H₂O: 2 mg/mL, clear (warmed)
• storage temp.: 2-8°C

Description

Biochem/physiol Actions

MitoCDNB is a mitochondrially selective inactivator of mitochondrial thiol redox homeostasis in isolated cells and in vivo. MitoCDNB selectively depletes the mitochondrial reduced glutathione (GSH) pool by formation of MitoGSDNB and dramatically increasing absorbance at 328 nm. It directly inhibits mitochondrial thioredoxin TrxR2 and peroxiredoxin 3.

mitochondrially selective inactivator of mitochondrial thiol redox homeostasis in isolated cells and in vivo

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable