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SML1941

CGP3466B maleate salt

≥98% (HPLC)

Synonym(s):

CGP 3466B, Dibenz[b,f]oxepin-10-methanamine, N-methyl-N-2-propyn-1-yl-, (2Z)-2-butenedioate (1:1), N-(Dibenz[b,f]oxepin-10-ylmethyl)-N-methyl-N-(2-propynyl)amine monomaleic acid salt, Omigapil maleate salt, TCH346

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$98.40
25 mg

Available to ship TODAYfromMILWAUKEE

$397.00

About This Item

Empirical Formula (Hill Notation):
C19H17NO · C4H4O4
CAS Number:
Molecular Weight:
391.42
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

$98.40


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

N(CC1=Cc2c(cccc2)Oc3c1cccc3)(CC#C)C.OC(=O)\C=C/C(=O)O

InChI

1S/C19H17NO.C4H4O4/c1-3-12-20(2)14-16-13-15-8-4-6-10-18(15)21-19-11-7-5-9-17(16)19;5-3(6)1-2-4(7)8/h1,4-11,13H,12,14H2,2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

SQAZQLMBEHYFJA-BTJKTKAUSA-N

Biochem/physiol Actions

CGP3466B, also known as Omigapil maleate and TCH346, is a potent inhibitor of glyceraldehyde-3-phosphate dehydrogenase (GAPDH). It has been shown to have neuroprotective activity and received U.S. FDA Fast Track Designation for the treatment of congenital muscular dystrophy in May 2016.
Inhibitor of glyceraldehyde-3-phosphate dehydrogenase (GAPDH), neuroprotective.

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This Item
O111W108P5514
assay

≥98% (HPLC)

assay

-

assay

-

assay

-

form

powder

form

solid

form

powder

form

powder

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

-

solubility

DMSO: 2 mg/mL, clear

solubility

45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: >21 mg/mL

solubility

H2O: 25 mg/mL

solubility

-

color

white to beige

color

white

color

white

color

-


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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