SAB3500039

Anti-MATN1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution, ab2

• Synonim(y): Anti-CMP, Anti-CRTM, Anti-Cartilage matrix protein, Anti-Matrilin 1
• Kod UNSPSC: 12352203
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• białko sprzężone: unconjugated
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• Postać: buffered aqueous solution
• reaktywność gatunkowa: mouse, human, rat
• metody: indirect ELISA: suitable; western blot: suitable
• numer dostępu NCBI: NP_002370
• numer dostępu UniProt: P21941
• Warunki transportu: dry ice
• temp. przechowywania: −20°C
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... MATN1(4146)

Opis

Immunogen

MATN1 antibody was raised against a 12 amino acid peptide from near the amino terminus of human MATN1.

Cechy i korzyści

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Opis wartości docelowych

Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN1 is composed of two Willebrand Factor A (vWFA) domains separated by one EGF-like domain, whereas MATN3 is composed of a single N-terminal vWFA domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that the MATN1 promoter region was associated with both susceptibility and disease progression in Adolescent idiopathic scoliosis.

Powiązanie

The action of this antibody can be blocked using blocking peptide SBP3500039.

Postać fizyczna

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable