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Merck

RAB0140

Human Decorin ELISA Kit

for serum, plasma, cell culture supernatant and urine

Synonim(y):

Decorin

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Informacje o tej pozycji

NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... DCN(1634)
Input:
sample type cell culture supernatant(s)
sample type urine
sample type serum
sample type plasma
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
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species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable, capture ELISA: suitable

input

sample type cell culture supernatant(s)
sample type urine
sample type serum
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1.5 pg/mL
standard curve range: 0.96-700 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... DCN(1634)

General description

Decorin comprises dermatan sulfate or a chondroitin sulfate chain. It belongs to the small leucine-rich proteoglycan (SLRP) gene family and is expressed majorly in the myofibroblasts and fibroblasts.
The Human Decorin ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human Decorin in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human Decorin

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human Decorin ELISA Kit has been used in sandwich enzyme-linked immunosorbent assay (ELISA) of mice serum. It has also been used in the ELISA of plasma samples and cerebrospinal fluid (CSF) of glioma patients.

Biochem/physiol Actions

Decorin is involved in a wide variety of biological processes including cell differentiation, growth and muscle development. It also takes part in wound healing, angiogenesis and regulates autophagy and inflammation. Decorin interacts with matrix proteins and inhibits tumor migration and growth.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
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Elementy zestawu są też dostępne oddzielnie

Numer produktu
Opis
Karta charakterystyki

  • RABELADEELISA 5X Assay/Sample Diluent Buffer E (Item E2)Karta charakterystyki

  • RABSTOP3ELISA Stop Solution (Item I)Karta charakterystyki

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)Karta charakterystyki

  • RABWASH420X Wash Buffer (Item B)Karta charakterystyki

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Klasa składowania

10 - Combustible liquids


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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Mohammad F Siddiqui et al.
American journal of obstetrics and gynecology, 215(3), 361-361 (2016-03-24)
Decorin, a leucine-rich proteoglycan that is produced by decidual cells, limits invasion and endovascular differentiation of extravillous trophoblast cells during early placentation by binding to multiple tyrosine kinase receptors, in particular, vascular endothelial growth factor receptor-2. Because many studies have
Andrea Reszegi et al.
Frontiers in oncology, 10, 645-645 (2020-06-02)
Hepatocellular carcinoma (HCC) represents one of the most frequent type of primary liver cancers. Decorin, a small leucine-rich proteoglycan of the extracellular matrix, represents a powerful tumor cell growth and migration inhibitor by hindering receptor tyrosine kinases and inducing p21WAF1/CIP1.
Dong-Ming Kuang et al.
The Journal of clinical investigation, 124(10), 4657-4667 (2014-09-23)
Classical IL-22-producing T helper cells (Th22 cells) mediate inflammatory responses independently of IFN-γ and IL-17; however, nonclassical Th22 cells have been recently identified and coexpress IFN-γ and/or IL-17 along with IL-22. Little is known about how classical and nonclassical Th22
Andrea Reszegi et al.
Biomolecules, 10(8) (2020-08-23)
Decorin, the prototype member of the small leucine-rich proteoglycan gene family of extracellular matrix (ECM) proteins, acts as a powerful tumor suppressor by inducing the p21Waf1/Cip1 cyclin-dependent kinase inhibitor, as well as through its ability to directly bind and block
Ting Yao et al.
FEBS open bio, 6(7), 707-719 (2016-07-12)
Decorin (DCN) is a major member of the small leucine-rich proteoglycan (SLRP) family that is critically involved in tumorigenesis and the development of metastasis of cancers, including glioma. Overexpression of DCN was indicated to suppress glioma cell growth. However, the

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