M4670
D-Mannosamine hydrochloride
≥98% (HPLC)
Synonim(y):
2-Amino-2-deoxy-D-mannose hydrochloride
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Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C6H13NO5 · HCl
Numer CAS:
Masa cząsteczkowa:
215.63
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
EC Number:
226-847-8
Beilstein/REAXYS Number:
3914860
MDL number:
Pomoc techniczna
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Pozwól nam pomócPomoc techniczna
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Pozwól nam pomócQuality Level
biological source
crab (shell), shrimp shells
assay
≥98% (HPLC)
form
powder
technique(s)
HPLC: suitable
color
white
mp
168 °C (dec.) (lit.)
solubility
water: 50 mg/mL, clear, colorless to faintly yellow
storage temp.
2-8°C
SMILES string
Cl[H].N[C@@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
InChI
1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3+,4-,5-,6?;/m1./s1
InChI key
QKPLRMLTKYXDST-OHXGPSCHSA-N
Application
D-Mannosamine hydrochloride can be used for the synthesis of non-natural ManNAc analogs for the expression of thiols on cell-surface sialic acids. It has been used in a study to investigate the synthesis and high-throughput screening of N-acetyl-β-hexosaminidase inhibitor libraries targeting osteoarthritis.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
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Klasa składowania
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
Srinivasa-Gopalan Sampathkumar et al.
Nature protocols, 1(5), 2377-2385 (2007-04-05)
The sialic acid biosynthetic pathway in mammalian cells utilizes N-acetyl-D-mannosamine (ManNAc) as a natural metabolic precursor and has the remarkable ability to biosynthetically process non-natural ManNAc analogs. Herein, we describe a recipe-style protocol for the synthesis of the novel peracetylated
Junjie Liu et al.
The Journal of organic chemistry, 69(19), 6273-6283 (2004-09-11)
C1 Nitrogen iminocyclitols are potent inhibitors of N-acetyl-beta-hexosaminidases. Given hexosaminidases' important roles in osteoarthritis, we developed two straightforward and efficient syntheses of C1 nitrogen iminocyclitols from two readily available starting materials, D-mannosamine hydrochloride and the microbial oxidation product of fructose.
Tal Gefen et al.
Vaccine, 28(51), 8197-8202 (2010-09-30)
Passive immunization with cross-species antibodies triggers the patient's immune response, thereby preventing repeated treatment. Mannosamine-biotin adduct (MBA) has been described as a masking agent for immunogenic reduction and here, the immunogenicity and biological activity of MBA-coated horse anti-viper venom (hsIgG)
Christopher Brigham et al.
Journal of bacteriology, 191(11), 3629-3638 (2009-03-24)
We characterized the nanLET operon in Bacteroides fragilis, whose products are required for the utilization of the sialic acid N-acetyl neuraminic acid (NANA) as a carbon and energy source. The first gene of the operon is nanL, which codes for
Monica De Caroli et al.
The Plant journal : for cell and molecular biology, 65(2), 295-308 (2011-01-13)
The secretory pathway in plants involves sustained traffic to the cell wall, as matrix components, polysaccharides and proteins reach the cell wall through the endomembrane system. We studied the secretion pattern of cell-wall proteins in tobacco protoplasts and leaf epidermal
Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| M4670-100MG | 04061832391830 |
| M4670-10MG | 04061832391847 |
| M4670-1G | 04061826060582 |
| M4670-500MG | 04061832391854 |
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