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E7159

Exo2

≥98% (HPLC)

Synonym(s):

2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol

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5 mg

Available to ship TODAYfromMILWAUKEE

$101.00
$85.85

About This Item

Empirical Formula (Hill Notation):
C18H18N4O2S
CAS Number:
304684-77-3
Molecular Weight:
354.43
NACRES:
NA.77
PubChem Substance ID:
329799006
UNSPSC Code:
12352200
MDL number:
MFCD00380179
Assay:
≥98% (HPLC)
Form:
powder

$85.85

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assay

≥98% (HPLC)

form

powder

color

yellow

solubility

DMSO: >20 mg/mL

storage temp.

2-8°C

SMILES string

COc1cc(ccc1O)\C=N\Nc2ncnc3sc4CCCCc4c23

InChI

1S/C18H18N4O2S/c1-24-14-8-11(6-7-13(14)23)9-21-22-17-16-12-4-2-3-5-15(12)25-18(16)20-10-19-17/h6-10,23H,2-5H2,1H3,(H,19,20,22)/b21-9+

InChI key

VFNUTEMVQGLDAG-ZVBGSRNCSA-N

Biochem/physiol Actions

Exo2 acts as a chemical probe of intracellular transport.
Exo2 acts as a chemical probe of intracellular transport. Edxo2 has activities similar to Brefeldin A with membrane trafficking to the Golgi appartus, but appears more selective.
Exo2 is a bioactive small molecule that activates Golgi-endoplasmic reticulum (ER) fusion in mammals by distorting the Golgi apparatus. It prevents the release of secretory cargo from the ER. Exo2 do not modify the morphology of the trans-Golgi network (TGN).[1] It also inhibits the anterograde movement of vesicular stomatitis virus G (VSV G) glycoprotein, from ER to Golgi.[2]

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X3004SML1741SML1419
Exo2 ≥98% (HPLC)

Sigma-Aldrich

E7159

Exo2

XAV939 ≥98% (HPLC)

Sigma-Aldrich

X3004

XAV939

TH1020 ≥95% (HPLC)

Sigma-Aldrich

SML1741

TH1020

B32B3 ≥95% (HPLC)

Sigma-Aldrich

SML1419

B32B3

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥95% (HPLC)

assay

≥95% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

room temp

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: >20 mg/mL

solubility

DMSO: 5 mg/mL, clear

solubility

DMSO: 3 mg/mL, clear (warmed)

solubility

DMSO: 10 mg/mL, clear

color

yellow

color

white to beige

color

white to beige

color

light yellow to dark yellow

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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