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Merck

D2022

Sigma-Aldrich

5,6-Dihydrothymidine

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About This Item

Wzór empiryczny (zapis Hilla):
C10H16N2O5
Numer CAS:
Masa cząsteczkowa:
244.24
Numer MDL:
Kod UNSPSC:
12352204

temp. przechowywania

−20°C

ciąg SMILES

CC1CN(C2CC(O)C(CO)O2)C(=O)NC1=O

Kod klasy składowania

13 - Non Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)


Certyfikaty analizy (CoA)

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

M A Chaudhry et al.
Journal of molecular biology, 249(5), 914-922 (1995-06-23)
Energy deposition by ionizing radiation can lead to the formation of clustered DNA damage, i.e. more than one lesion situated within a helical turn of DNA. Among the postulated lesions are those characterized by damaged bases and abasic sites on
E A Furlong et al.
Biochemistry, 25(15), 4344-4349 (1986-07-29)
5,6-Dihydrothymidine (dDHT) is a derivative thymidine formed during gamma-irradiation. This paper demonstrates the conditions under which dDHT is formed in solutions of DNA and that dDHT is produced in the DNA of HeLa cells during gamma-irradiation. The product of dDHT
Marie-Hélène David-Cordonnier et al.
Biochemistry, 41(2), 634-642 (2002-01-10)
A major DNA lesion induced by ionizing radiation and formed on removal of oxidized base lesions by various glycosylases is an apurinic/apyrimidinic site (AP site). The presence of an AP site within clustered DNA damage, induced following exposure to ionizing
J Cadet et al.
International journal of radiation biology and related studies in physics, chemistry, and medicine, 39(2), 119-133 (1981-02-01)
The steady-state gamma radiolysis of deaerated aqueous solutions of thymidine generated a complex mixture of pyrimidine and nucleoside derivatives. Twenty-two of these compounds have been isolated and unambiguously characterized by spectroscopic methods including proton nuclear magnetic resonance and mass spectrometry.
M Weinfeld et al.
Nucleic acids research, 21(3), 621-626 (1993-02-11)
Stacking between aromatic amino acids and nucleic acid bases may play an important role in the interaction of enzymes with nucleic acid substrates. In such circumstances, disruption of base aromaticity would be expected to decrease enzyme activity on the modified

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