α-Dansyl-L-arginina zawiera N-końcowy fluorofor (dansyl), dzięki czemu jest przydatna jako marker/sonda fluorescencyjna. α-Dansyl-L-arginina jest stosowana jako marker specyficzny dla miejsca wiązania leku na białkach. α-Dansyl-L-arginina, dansyl-l-asparagina i dansyl-l-glutaminian są specyficzne dla miejsca wiązania leku 1 na albuminie (HSA).
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The effects of dansyl-arginyl-(4'-ethyl)-piperidine amide (DAPA) on the binding of gonadotropins has been investigated. The compound inhibited the binding of hCG, human LH, and porcine LH to rat luteal membranes with an ED50 of 70 microM and the binding of
Continuous zone electrophoretic separations in narrow channels coupled to small-bore capillaries have been demonstrated and characterized previously. Presented here is the use of this new technique to monitor dynamic chemical changes occurring in a flow injection analysis system. The fundamental
The Journal of pharmacy and pharmacology, 46(4), 300-304 (1994-04-01)
Human serum albumin is known to have two major and selective drug binding sites, termed sites I and II. The fluorescent probes, dansylamide and dansylsarcosine selectively interact with sites I and II, respectively. However, the binding site of the fluorescent
Journal of structural biology, 174(1), 84-91 (2010-10-14)
Human serum albumin (HSA) has two primary binding sites for drug molecules. These sites selectively bind different dansylated amino acid compounds, which-due to their intrinsic fluorescence-have long been used as specific markers for the drug pockets on HSA. We present
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