C2105

Z-Val-Ala-Asp fluoromethyl ketone

Name: Z-Val-Ala-Asp fluoromethyl ketone
Brand: SIGMA
Price: 2530 PLN

≥90% (TLC), Caspase-1 inhibitor, powder

Synonim(y):

Z-VAD-FMK, Non-methylated

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3 MG

2530,00 zł

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Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):

C₂₁H₂₈FN₃O₇

Numer CAS:

161401-82-7

Masa cząsteczkowa:

453.46

UNSPSC Code:

12352209

PubChem Substance ID:

329774926

NACRES:

NA.77

MDL number:

MFCD03452883

Assay:

≥90% (TLC)

Form:

powder

Quality level:

200

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Nazwa produktu

Z-Val-Ala-Asp fluoromethyl ketone, powder, ≥90% (TLC)

SMILES string

CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)CF

InChI

1S/C21H28FN3O7/c1-12(2)18(25-21(31)32-11-14-7-5-4-6-8-14)20(30)23-13(3)19(29)24-15(9-17(27)28)16(26)10-22/h4-8,12-13,15,18H,9-11H2,1-3H3,(H,23,30)(H,24,29)(H,25,31)(H,27,28)/t13-,15-,18-/m0/s1

InChI key

SUUHZYLYARUNIA-YEWWUXTCSA-N

assay

≥90% (TLC)

form

powder

shipped in

dry ice

storage temp.

−20°C

Quality Level

200

Powiązane kategorie

Bioactive Small Molecule Inhibitors

Bioactive Small Molecules

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Ta pozycja	C1480	C1230	B2682
Sigma-Aldrich C2105 Z-Val-Ala-Asp fluoromethyl ketone	Sigma-Aldrich C1480 Z-Phe-Ala fluoromethyl ketone	Sigma-Aldrich C1230 Z-Ile-Glu(O-ME)-Thr-Asp(O-Me) fluoromethyl ketone	Sigma-Aldrich B2682 Boc-Asp(OMe)-fluoromethyl ketone
assay ≥90% (TLC)	assay ≥90% (TLC)	assay ≥90% (TLC)	assay ≥90% (TLC)
form powder	form powder	form powder	form solid
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 100
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
shipped in dry ice	shipped in dry ice	shipped in dry ice	shipped in -

Biochem/physiol Actions

Non-methylated competitive and irreversible inhibitor of caspase-1, as well as other caspases, which can be used directly with purified enzymes. It does not require esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(OMe) fluoromethyl ketone (Product Code V-116).

Features and Benefits

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Klasa składowania

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Z-Val-Ala-Asp fluoromethyl ketone