92107

O-Acetyl-L-carnitine hydrochloride

analytical standard

• Synonim(y): (R)-3-Acetoxy-4-(trimethylammonio)butyrate hydrochloride, ALC, ALCAR, R-(−)-2-Acetyloxy-3-carboxy-N,N,N-trimethyl-1-propanaminium chloride
• Wzór empiryczny (zapis Hilla): C₉H₁₇NO₄ · HCl
• Numer CAS: 5080-50-2
• Masa cząsteczkowa: 239.70
• NACRES: NB.21
• UNSPSC Code: 41116107
• Beilstein/REAXYS Number: 4340103
• MDL number: MFCD00082230

Właściwości

• grade: analytical standard
• Quality Segment: 100
• assay: ≥96.0% (HPLC), 96.0-104.0% (AT)
• form: powder or crystals
• optical activity: [α]/D -27.0±2.0°, c = 1 in H₂O
• shelf life: limited shelf life, expiry date on the label
• color: white to off-white
• application(s): clinical testing
• format: neat
• storage temp.: 2-8°C
• SMILES string: C[N+](C)(C)C[C@H](OC(C)=O)CC(O)=O.[Cl-]
• InChI: 1S/C9H17NO4.ClH/c1-7(11)14-8(5-9(12)13)6-10(2,3)4;/h8H,5-6H2,1-4H3;1H/t8-;/m1./s1
• InChI key: JATPLOXBFFRHDN-DDWIOCJRSA-N

Opis

General description

Acetyl carnitine is one of the major acylcarnitines produced during the transport of long-chain fatty acids in the body.

Application

O-Acetyl-L-carnitine hydrochloride may be used as a precursor for the preparation of O-Acetyl-L-carnitine, which in turn may be used as an analytical reference standard for the determination of the analyte in biological samples by hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS) technique.

Biochem/physiol Actions

Endogenous mitochondrial metabolite that transports acetyl groups across the mitochondrial membrane.

Endogenous mitochondrial metabolite that transports acetyl groups across the mitochondrial membrane. Exogenous acetylcarnitine enhances mitochondrial function in aged rats. As an acetate donor to coenzyme A, it increases the central and peripheral acetylcholine synthesis and function. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable