53797

Chlordane (mixture of isomers)

certified reference material, TraceCERT^®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

• Numer CAS: 57-74-9
• MDL number: MFCD00036125
• UNSPSC Code: 41116107
• NACRES: NA.24

Właściwości

• Quality Segment: 300
• description: technical mixture
• product line: TraceCERT^®
• grade: certified reference material, TraceCERT^®
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
• format: neat
• storage temp.: −20°C
• SMILES string: ClC21C3C(C(C2(Cl)Cl)(C(=C1Cl)Cl)Cl)CC(C3Cl)Cl
• InChI: 1S/C10H6Cl8/c11-3-1-2-4(5(3)12)9(16)7(14)6(13)8(2,15)10(9,17)18/h2-5H,1H2
• InChI key: BIWJNBZANLAXMG-UHFFFAOYSA-N

Opis

General description

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ. Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate. Download your certificate at: http://www.sigma-aldrich.com.

Chlordane is a synthetic organochlorine pesticide that belongs to the group of chlorinated cyclodiene. They are commonly resistant to photolytic, chemical, and biological degradation, and have relatively long half-lives. Chlordane manufactured as a technical form is composed of more than 120 structurally related compounds. The predominant isomers in technical chlordane are cis-chlordane (19%), trans-chlordane (24%), cis-nonachlor (2.7%), trans-nonachlor (9.7%), and heptachlor (10%).

Chlordane has to be monitored in the Multiannual Control Programmes for Pesticides Residues (MACP), run within the EU and EFTA in/on products of animal origin. Maximum residue levels (MRLs) have been set according to Reg (EC) No 149/2008 for chlordane (sum of cis-and trans chlordane) for various products of plant and animal origin from 0.01 to 0.005 mg/kg.

Technical chlordane was used mostly as an agricultural pesticide on corn and citrus, for home lawns and gardens, as well as a termiticide in house foundation. Chlordane blocks the gamma-aminobutyric acid (GABA)-gated chloride channels in the central nervous system, resulting in hyperexcitation and convulsions.

The use of chlordane as a pesticide has been banned in the EU since 1981 by Council Directive 79/117/EEC of 21 December 1978 which prohibited the placing on the market and use of plant protection products containing certain substances.

Application

It is intended to be used as a certified reference material (CRM) for calibration in chromatography and other analytical techniques. Chlordane in CRM may also find its use as described below:

• Study of joint toxic effects of polystyrene nanoparticles and chlordane and hexachlorocyclohexane pesticides on Caenorhabditis elegans
• Development of biomonitoring equivalents for chlordane and toxaphene with application to the general Canadian population
• To study chlordane, PCBs, and synthetic musk fragrances in a backwater area in the Upper Mississippi River and Iowa River
• QuEChERS method and a single instrumental analysis to detect a broad range of persistent organic pollutants (POPs) in white sturgeon liver and gonad tissues as an indication of exposure
• To investigate the effect of chlordane, heptachlor, and mirex, on hormonal regulation of the force of myometrial contractions in cow

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• pictograms: GHS06,GHS08,GHS09
• signalword: Danger
• hcodes: H301 + H311,H351,H410
• pcodes: P202 - P264 - P273 - P280 - P301 + P310 - P302 + P352 + P312
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3