15527

Glycine

meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)

• Synonim(y): Aminoacetic acid, Aminoethanoic acid, Glycocoll
• Wzór liniowy: NH₂CH₂COOH
• Numer CAS: 56-40-6
• Masa cząsteczkowa: 75.07
• NACRES: NA.21
• PubChem Substance ID: 57647473
• eCl@ss: 32160406
• UNSPSC Code: 12352209
• EC Number: 200-272-2
• MDL number: MFCD00008131
• Beilstein/REAXYS Number: 635782

Właściwości

• Quality Level: 200
• assay: 99-101% (based on anhydrous substance)
• form: crystalline powder
• quality: meets analytical specification of Ph. Eur., BP, USP
• technique(s): IR spectroscopy: suitable
• impurities: hydrolyzable substances, complies, organic volatile impurities, complies (GC), residual solvents, complies, ≤0.001% heavy metals (as Pb), ≤1.0% ninhydrin-positive substances
• ign. residue: ≤0.1% (as SO₄)
• loss: ≤0.2% loss on drying, 105 °C, 2 h
• color: white
• pH: 5.9-6.4 (20 °C, 5%)
• pKa (25 °C): (1) 2.35, (2) 9.60, 2.35
• mp: 240 °C (dec.) (lit.)
• solubility: H₂O: soluble 25 gm in 100 ml at 25 degrees c, H₂O: soluble 39.1 gm in 100 ml at 50 degrees c, alcohol: soluble 0.06 gm in 100 gm (Absolute), pyridine: soluble 164 parts, alcohol: very slightly soluble, diethyl ether: very slightly soluble
• anion traces: chloride (Cl^-): ≤50 mg/kg, sulfate (SO₄^2-): ≤50 mg/kg
• suitability: complies for appearance of solution, complies for reaction against H₂SO₄, in accordance for identity (IR)
• SMILES string: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• InChI key: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Gene Information: rat ... Grin2a(24409)

Opis

Application

Glycine was used for preparing platelets from whole-blood samples and study the stimulation of cytokine expression in leukocytes.[1] It was used for biochemical and tolerance tests.[2]

Biochem/physiol Actions

Glycine has a pivotal role in lowering the plasma lipid levels in diabetic and obese patients by activating the CNS.[3] During brain hypoxia glycine can stabilize the energetics disturbances in brain mitochondria.[4] It also increases the in vitro development of porcine blastocysts when used along with glucose.[5]

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• ppe: Eyeshields, Gloves, type N95 (US)
• flash_point_f: No data available
• flash_point_c: No data available