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MAB4162

Anti-MDR1 Antibody, extracellular human specific Pgp, clone MM4.17

clone MM4.17, Chemicon®, from mouse

Synonim(y):

P-glycoprotein, CD243, p170, Pgp

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Gabaryty przesyłkiSKUDostępnośćCena netto
100 μg

Przewidywany termin wysyłki26 maja 2026zKuehne + Nagel Sp. z o.o.

2760,00 zł

Informacje o tej pozycji

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
MM4.17, monoclonal
Species reactivity:
human
Application:
FACS, IHC
Citations:
5

2760,00 zł


Przewidywany termin wysyłki26 maja 2026Szczegóły

Rekombinowane, niezawierające konserwantów przeciwciało jest dostępne dla Twojego celu. Wypróbuj ZRB1521

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biological source

mouse

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

MM4.17, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable, immunohistochemistry: suitable

isotype

IgG2aκ

NCBI accession no.

UniProt accession no.

shipped in

wet ice

Application

Anti-MDR1 Antibody, extracellular human specific Pgp, clone MM4.17 is an antibody against MDR1 for use in FC, IH.
Flow Cytometry

Immunohistochemistry on formalin fixed paraffin embedded sections

Confocal and Electron Microscopy

ELISA

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Recognizes a mapped epitope in the extracellular Pgp domain and detects low-level Pgp expression in living (intact) human MDR cells (Cianfriglia, 2002). The epitope has been mapped to the single amino acid level using different techniques (Cianfriglia, 1994 and Poloni, 1995).

Physical form

Format: Purified

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Ta pozycja
MAB4334ZMAB4120P7965
clone

MM4.17, monoclonal

clone

UIC2, monoclonal

clone

JSB-1, monoclonal

clone

F4, monoclonal

species reactivity

human

species reactivity

primate, human

species reactivity

human, hamster

species reactivity

hamster, human

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

culture supernatant

antibody form

ascites fluid

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

UniProt accession no.

P08183

UniProt accession no.

P08183

UniProt accession no.

P08183

UniProt accession no.

P08183

technique(s)

flow cytometry: suitable, immunohistochemistry: suitable

technique(s)

flow cytometry: suitable, immunofluorescence: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable

technique(s)

flow cytometry: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable (paraffin), western blot: suitable

technique(s)

immunocytochemistry: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:500 using human kidney sections, immunohistochemistry (frozen sections): suitable, immunoprecipitation (IP): suitable, indirect ELISA: suitable, radioimmunoassay: suitable using cell-surface RIA, western blot: suitable


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wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Klasa składowania

12 - Non Combustible Liquids



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Powiązane treści


Paola Turella et al.
The Journal of biological chemistry, 281(33), 23725-23732 (2006-06-14)
The new glutathione S-transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) is cytotoxic toward P-glycoprotein-overexpressing tumor cell lines, i.e. CEM-VBL10, CEM-VBL100, and U-2 OS/DX580. The mechanism of cell death triggered by NBDHEX has been deeply investigated in leukemia cell lines. Kinetic data indicate a
Jingwei Zhang et al.
British journal of pharmacology, 165(1), 120-134 (2011-05-28)
Intracellular pharmacokinetics of anticancer drugs in multi-drug resistance (MDR) cancer cells is hugely important in the evaluation and improvement of drug efficacy. By using adriamycin as a probe drug in MDR cancer cells, we developed a cellular pharmacokinetic-pharmacodynamic (PK-PD) model
Marine Chartrain et al.
PloS one, 7(5), e36762-e36762 (2012-06-08)
Metastatic melanoma is the most aggressive skin cancer. Recently, phenotypically distinct subpopulations of tumor cells were identified. Among them, ABCB5-expressing cells were proposed to display an enhanced tumorigenicity with stem cell-like properties. In addition, ABCB5(+) cells are thought to participate



Numer pozycji handlu globalnego

SKUNUMER GTIN
MAB416204053252660290

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