8.52407

Fmoc-Lys(Boc)-(Dmb)Gly-OH

Novabiochem^®

• Synonim(y): Fmoc-Lys(Boc)-(Dmb)Gly-OH
• Wzór empiryczny (zapis Hilla): C₃₇H₄₅N₃O₉
• Masa cząsteczkowa: 675.77
• Kod UNSPSC: 12352209
• NACRES: NA.22

Właściwości

• Poziom jakości: 200
• linia produktu: Novabiochem^®
• Postać: powder
• przydatność reakcji: reaction type: Fmoc solid-phase peptide synthesis
• producent / nazwa handlowa: Novabiochem^®
• Zastosowanie: peptide synthesis
• grupa funkcyjna: amine
• temp. przechowywania: 2-8°C

Opis

Opis ogólny

Fmoc-Aaa-(Dmb)Gly-OH dipeptides offer the same benefits aspseudoproline dipeptides such as prevention of aggregation and improvements in product quality but for peptide sequences containing Gly. They are extremely easy to use. Standard coupling methods like PyBOP^®/DIPEA or DIPCDI/HOBt can be used for their introduction. Removal of the Dmb group and regeneration of the glycine residue occurs during the course of standard TFA-mediated cleavage reaction.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Overcoming Aspartimide Formation in Fmoc SPPS

Komentarz do analizy

Color (visual): white to off white
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in methanol): -21.0 - -17.0 °
Purity (TLC(157A)): ≥ 98 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 90.0 %
Water (K. F.): ≤ 1.50 %
Ethyl acetate (HS-GC): ≤ 1.0 %
Acetate (IC): ≤ 0.02 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Informacje prawne

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable