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539470

Proteinase K Inhibitor

Proteinase K Inhibitor is a tetrapeptidyl chloromethyl ketone compound that acts as an active-site-targeting irreversible inhibitor against proteinase K.

Synonim(y):

Proteinase K Inhibitor, MeOSuc-AAPF-CMK

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Gabaryty przesyłkiSKUDostępnośćCena netto

Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C26H35ClN4O7
Masa cząsteczkowa:
551.03
NACRES:
NA.54
UNSPSC Code:
12352202
Assay:
≥97% (HPLC)
Form:
lyophilized
Quality level:
200
Storage condition:
OK to freeze, desiccated, protect from light
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Quality Level

200

assay

≥97% (HPLC)

form

lyophilized

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated, protect from light

solubility

DMSO: 3 mg/mL

shipped in

ambient

storage temp.

−20°C

General description

A tetrapeptidyl chloromethyl ketone compound that acts as an active-site-targeting irreversible inhibitor against proteinase K (Cat. Nos. 539480, 70663, & 71049). Shown to be more potent than MeOSuc-AAPV-CMK (Cat. Nos. 324745) in preventing the degradation of reverse transcriptase and albumin by proteinase K.

Packaging

Packaged under inert gas

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 week at -20°C.

Other Notes

Kore, A.R., et al. 2009. Bioorg. Med. Chem. Lett.19, 1296.
MeOSuc-Ala-Ala-Pro-Phe-CH₂Cl

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)
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Ta pozycja
219381219377219379
Proteinase K Inhibitor Proteinase K Inhibitor is a tetrapeptidyl chloromethyl ketone compound that acts as an active-site-targeting irreversible inhibitor against proteinase K.

Sigma-Aldrich

539470

Proteinase K Inhibitor

Cathepsin K Inhibitor III The Cathepsin K Inhibitor III controls the biological activity of Cathepsin K. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Sigma-Aldrich

219381

Cathepsin K Inhibitor III

Cathepsin K Inhibitor I The Cathepsin K Inhibitor I controls the biological activity of Cathepsin K. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Sigma-Aldrich

219377

Cathepsin K Inhibitor I

Cathepsin K Inhibitor II The Cathepsin K Inhibitor II controls the biological activity of Cathepsin K. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Sigma-Aldrich

219379

Cathepsin K Inhibitor II

form

lyophilized

form

lyophilized solid

form

lyophilized solid

form

lyophilized solid

assay

≥97% (HPLC)

assay

≥97% (HPLC)

assay

≥95% (HPLC)

assay

≥95% (HPLC)

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage condition

OK to freeze, protect from light, desiccated

storage condition

OK to freeze, desiccated (hygroscopic)

storage condition

OK to freeze

storage condition

OK to freeze

Klasa składowania

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certyfikaty analizy (CoA)

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Darci Phillips et al.
Nature communications, 12(1), 6726-6726 (2021-11-20)
Cutaneous T cell lymphomas (CTCL) are rare but aggressive cancers without effective treatments. While a subset of patients derive benefit from PD-1 blockade, there is a critically unmet need for predictive biomarkers of response. Herein, we perform CODEX multiplexed tissue
Julia Joung et al.
Nature communications, 13(1), 1606-1606 (2022-03-27)
The cellular processes that govern tumor resistance to immunotherapy remain poorly understood. To gain insight into these processes, here we perform a genome-scale CRISPR activation screen for genes that enable human melanoma cells to evade cytotoxic T cell killing. Overexpression

Numer pozycji handlu globalnego

SKUNUMER GTIN
539470-10MG04055977269109

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