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Merck

36-008

Anti-α-Synuclein (SNCA) Antibody

UPSTATE®, mouse monoclonal, Syn211

Synonim(y):

Anti-NACP, Anti-PARK1, Anti-PARK4, Anti-PD1

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Informacje o tej pozycji

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
Syn211, monoclonal
Species reactivity:
human
Application:
IHC, IP, WB
Citations:
29
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Nazwa produktu

Anti-α-Synuclein Antibody, clone Syn211, ascites fluid, clone Syn211, Upstate®

biological source

mouse

Quality Level

antibody form

ascites fluid

antibody product type

primary antibodies

clone

Syn211, monoclonal

species reactivity

human

packaging

antibody small pack of 25 μL

manufacturer/tradename

Upstate®

technique(s)

immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

ambient

target post-translational modification

unmodified

Gene Information

human ... SNCA(6622)

General description

~14.5kDa

Immunogen

full-length recombinant human α-Synuclein

Application

Detect α-Synuclein using this Anti-α-Synuclein Antibody, clone Syn211 validated for use in IP, WB, IH.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases

Biochem/physiol Actions

α-Synuclein

Physical form

Ascites

Preparation Note

2 years at -20°C

Analysis Note

Routinely evaluated by immunoblot on Alzheimer′s diseased human whole brain lysates.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Klasa składowania

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów



Jay S Schneider et al.
Molecular and cellular neurosciences, 120, 103729-103729 (2022-04-22)
Among the pathological events associated with the dopaminergic neurodegeneration characteristic of Parkinson's disease (PD) are the accumulation of toxic forms of α-synuclein and microglial activation associated with neuroinflammation. Although numerous other processes may participate in the pathogenesis of PD, the
Sarah M O'Donovan et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 32(1), e13726-e13726 (2019-10-03)
A hallmark feature of Parkinson's disease (PD) is the build-up of α-synuclein protein aggregates throughout the brain; however α-synuclein is also expressed in enteric neurons. Gastrointestinal (GI) symptoms and pathology are frequently reported in PD, including constipation, increased intestinal permeability
Rachel Kelly et al.
Molecules (Basel, Switzerland), 27(2) (2022-01-22)
Since the discovery of α-synuclein as the major component in Lewy bodies, research into this protein in the context of Parkinson's disease pathology has been exponential. Cannabinoids are being investigated as potential therapies for Parkinson's disease from numerous aspects, but



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SKUNUMER GTIN
36-008-25UL04054839337352