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23-029-M

UbcH5a Protein, active, 50 µg

Name: UbcH5a Protein, active, 50 µg
Brand: MM
Price: 866 PLN
Availability: InStock

Active, full length, recombinant human UbcH5a. N-terminal HA, 6His-tagged. For use in Enzyme Assays. Functions as an E2 enzyme in ubiquitination assays.

Synonim(y):

Ubiquitin-conjugating enzyme E2 D1, Ubiquitin-protein ligase D1, Ubiquitin-conjugating enzyme E2-17 kDa 1, UBC4/5 homolog, Stimulator of Fe transport (SFT), UbcH5, UBE2D1

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Do Państwa/SKU	Dostępność	Cena netto
50 μg	Przewidywany termin wysyłki26 maja 2026zKuehne + Nagel Sp. z o.o.	866,00 zł

Informacje o tej pozycji

UNSPSC Code:

12352202

NACRES:

NA.41

eCl@ss:

32160405

Biological source:

human

866,00 zł

Przewidywany termin wysyłki26 maja 2026Szczegóły

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Pomoc techniczna

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Pozwól nam pomóc

Właściwości

biological source

human

Quality Segment

100, 300

manufacturer/tradename

Upstate^®

technique(s)

activity assay: suitable

NCBI accession no.

NM_003338

Opis

General description

Ubiquitin-conjugating (E2) enzymes are characterized by the presence of a highly conserved ubiquitin-conjugating domain which accommodates ATP-activated ubiquitin (Ub) via a covalently linked thioester onto its active-site residue. E2 enzymes act via selective protein-protein interactions with the ubiquitin-activating E1 enzyme and ubiquitin ligase E3 enzymes and are able to differentiate effects on downstream substrates, either with a single Ub molecule or an Ub chain. While E3s are involved in substrate selection, E2s are the main determinants for selection of the lysine to construct Ub chains, which thereby directly control the cellular fate of the substrate. The UbcH5 family (UbcH5a, UbcH5b and UbcH5c) have been shown to be the most active class of E2 enzymes in cell extracts and are associated with the regulation of a number of transcription factors, including p53 and c-Myc.

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Ta pozycja	23-025-M	23-035-M	23-036-M
Sigma-Aldrich 23-029-M UbcH5a Protein, active, 50 µg	Sigma-Aldrich 23-025-M UbcH4 Protein, active, 50 µg	Sigma-Aldrich 23-035-M UbcH5c Protein, active, 10 µg	Sigma-Aldrich 23-036-M Białko UbcH6, aktywne, 10 µg
technique(s) activity assay: suitable	technique(s) activity assay: suitable	technique(s) activity assay: suitable	technique(s) activity assay: suitable
biological source human	biological source human	biological source human	biological source human
NCBI accession no. NM_003338	NCBI accession no. NM_003339	NCBI accession no. NM_181888	NCBI accession no. NM_003341
Quality Level 100, 300	Quality Level 100	Quality Level 100, 300	Quality Level 100, 300
manufacturer/tradename Upstate^®	manufacturer/tradename Upstate^®	manufacturer/tradename Upstate^®	manufacturer/tradename Upstate^®

pictograms

GHS07

signalword

Warning

hcodes

H317

pcodes

P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364

Hazard Classifications

Skin Sens. 1

Klasa składowania

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c