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Dokumenty

860102C

Avanti

16:0 Phosphatidylpropanol

Name: 16:0 Phosphatidylpropanol
Brand: AVANTI

1,2-dipalmitoyl-sn-glycero-3-phosphopropanol (sodium salt), chloroform

Synonim(y):

1,2-dihexadecanoyl-sn-glycero-3-phosphopropanol (sodium salt)

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About This Item

Wzór empiryczny (zapis Hilla):

C₃₈H₇₄O₈PNa

Numer CAS:

92609-91-1

Masa cząsteczkowa:

712.95

Kod UNSPSC:

12352211

NACRES:

NA.25

Próba

>99% (TLC)

Postać

liquid

opakowanie

pkg of 1 × 2.5 mL (860102C-25mg)

producent / nazwa handlowa

Avanti Research^™ - A Croda Brand 860102C

stężenie

10 mg/mL (860102C-25mg)

Warunki transportu

dry ice

temp. przechowywania

−20°C

InChI

1S/C38H75O8P.Na/c1-4-7-9-11-13-15-17-19-21-23-25-27-29-31-37(39)43-34-36(35-45-47(41,42)44-33-6-3)46-38(40)32-30-28-26-24-22-20-18-16-14-12-10-8-5-2;/h36H,4-35H2,1-3H3,(H,41,42);/q;+1/p-1/t36-;/m1./s1

Klucz InChI

SKVWIBXHTOHOAB-SKRAEFHRSA-M

Opis ogólny

Phosphatidylpropanol is a low polarity phospholipid. This phosphatidylalcohol can be produced by phospholipase D (PLD) catalyzed transphosphatidylation reaction of phosphatidylcholine (PC) and propanol.

Zastosowanie

16:0 Phosphatidylpropanol or 1,2-dipalmitoyl-sn-glycero-3-phosphopropanol may be used as an internal standard in ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) to evaluate its matrix effect in blood samples for the validation of phosphatidylethanol (PEth). It may also be used as an internal standard for the quantification of PEth using liquid chromatography-mass spectrometry (LC-MS) in human blood.

Działania biochem./fizjol.

Phosphatidylpropanol acts as a potential biomarker in phospholipase D activity assays.

Opakowanie

5 mL Clear Glass Sealed Ampule (860102C-25mg)

Informacje prawne

Avanti Research is a trademark of Avanti Polar Lipids, LLC

This page may contain text that has been machine translated.

Piktogramy

GHS06,GHS08

Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

H302,H315,H319,H331,H336,H351,H361d,H372,H412

Zwroty wskazujące środki ostrożności

P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313

Klasyfikacja zagrożeń

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Organy docelowe

Central nervous system, Liver,Kidney

Klasa zagrożenia wodnego (WGK)

WGK 3

Certyfikaty analizy (CoA)

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Odwiedź Bibliotekę dokumentów

Long-term stability of the alcohol consumption biomarker phosphatidylethanol in erythrocytes at- 80? C

Lakso H, et al.

Clinical mass spectrometry, 11(3), 37-41 (2019)

Sensitive and precise monitoring of phosphatidylethanol in human blood as a biomarker for alcohol intake by ultrasound-assisted dispersive liquid-liquid microextraction combined with liquid chromatography tandem mass spectrometry.

Siming Wang et al.

Talanta, 166, 315-320 (2017-02-19)

Phosphatidylethanol (PEth) is a special phospholipid that is only formed in the presence of ethanol, and therefore, serves as a promising biomarker for alcohol intake. In this study, a simple, rapid and precise method based on LC-MS/MS combined with ultrasound-assisted

TLC and 31P-NMR analysis of low polarity phospholipids.

Mikhail Vyssotski et al.

Lipids, 44(4), 381-389 (2008-12-17)

High-performance TLC and (31)P-NMR were assessed as methods of observing the presence of numerous low polarity phospholipids: bis-phosphatidic acid (BPA), semi-lyso bis-phosphatidic acid (SLBPA), N-acyl phosphatidylethanolamine (NAPE), N-(1,1-dimethyl-3-oxo-butyl)-phosphatidylethanolamine (diacetone adduct of PE, DOBPE), N-acetyl PE, phosphatidylmethanol (PM), phosphatidylethanol (PEt), phosphatidyl-n-propanol

Quantification of phosphatidylethanol 16:0/18:1, 18:1/18:1, and 16:0/16:0 in venous blood and venous and capillary dried blood spots from patients in alcohol withdrawal and control volunteers.

Natalie Kummer et al.

Analytical and bioanalytical chemistry, 408(3), 825-838 (2015-11-26)

Phosphatidylethanol species (PEths) are promising biomarkers of alcohol consumption. Here, we report on the set-up, validation, and application of a novel UHPLC-ESI-MS/MS method for the quantification of PEth 16:0/18:1, PEth 18:1/18:1, and PEth 16:0/16:0 in whole blood (30 μL) and

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