To develop a robust radiolabeling technique to enable evaluation of difficult to radiolabel gastric retentive formulations using gamma scintigraphy. The use of a successful radiolabel will allow accurate assessment of the gastric residence time of the formulations. The retention of
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 60(4), 933-939 (2004-03-24)
Microphone based photoacoustic (PA) spectrometer to study solids in powder form was designed and fabricated. Laser PA spectra of Sm3+ ion in Sm2O3 and SmCl3.6H2O microcrystalline powders were recorded first time in 484-542 nm spectral region at room temperature. Analysis
Journal of biomedical materials research. Part A, 94(1), 130-136 (2010-02-04)
The biocompatibility of natural samarium (III) oxide, which has previously been used for treatment in bone-related diseases was determined as a first step in its evaluation as a bone implant material. Assessment for 28 days using osteoblast-like cells revealed no
International journal of pharmaceutics, 281(1-2), 3-10 (2004-08-04)
This paper is a report from a pharmacoscintigraphic study with an Egalet constant-release system containing caffeine and natural abundance samarium oxide. First the formulation was tested in vitro to clarify integrity during irradiation in the nuclear reactor. Then six healthy
Journal of pharmaceutical sciences, 97(1), 225-236 (2007-08-28)
Treatment of systemic disease with phosphorothioate antisense oligonucleotides (PS ASOs) has been accomplished using local or parenteral routes of administration to date. This report describes, for the first time, the effective oral delivery of a second generation oligonucleotide where significant
Magnetic materials find diverse applications from data storage to renewable energy.
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